1.1.1.87: homoisocitrate dehydrogenase
This is an abbreviated version!
For detailed information about homoisocitrate dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.87
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1.1.1.87
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alpha-aminoadipate
-
3-isopropylmalate
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homocitrate
-
homoaconitase
-
beta-decarboxylating
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alpha-ketoadipate
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medicine
-
synthesis
- 1.1.1.87
- alpha-aminoadipate
- 3-isopropylmalate
- homocitrate
- homoaconitase
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beta-decarboxylating
- alpha-ketoadipate
- medicine
- synthesis
Reaction
Synonyms
(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating), 2-hydroxy-3-carboxyadipate dehydrogenase, 3-carboxy-2-hydroxyadipate dehydrogenase, 3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating), beta-decarboxylating dehydrogenase, dehydrogenase, homoisocitrate, EC 1.1.1.155, HIc, HIc dehydrogenase, HICDH, homoisocitrate dehydrogenase, homoisocitric dehydrogenase, isocitrate-homoisocitrate dehydrogenase, LYS12, protein PH1722, ScHICDH, TK0280
ECTree
1.1.1.87 homoisocitrate dehydrogenaseAdvanced search results
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results (Turnover Number
Turnover Number on EC 1.1.1.87 - homoisocitrate dehydrogenase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
171
1-hydroxy-1,2,3-propanetricarboxylate
-
purified enzyme, pH 8.0, 60°C
171
1-hydroxy-1,2,4-butanetricarboxylate
-
purified enzyme, pH 8.0, 60°C
0.099
D-malate
-
wild type enzyme, with NAD+ as cosubstrate, at pH 8.0 and 60°C
12
NADP+
-
wild type enzyme, with homoisocitrate as cosubstrate, at pH 8.0 and 60°C
0.59
trisodium (2S,3R)-2-(carboxylatomethoxy)-3-hydroxybutanedioate
-
-
2
trisodium (2S,3R)-2-[(carboxylatomethyl)amino]-3-hydroxybutanedioate
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-
0.38
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate
-
recombinant His-tagged enzyme, pH 7.8, 20°C
0.4
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate
-
native enzyme, pH 7.8, 20°C
0.78
(2R,3S)-3-(2-hydroxyethyl)malate
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pH 7.8, 36°C, recombinant enzyme
25
(2R,3S)-3-(2-hydroxyethyl)malate
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pH 7.8, 28°C, recombinant enzyme
4.8
(2R,3S)-3-(3-hydroxypropyl)malate
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pH 7.8, 36°C, recombinant enzyme
29
(2R,3S)-3-(3-hydroxypropyl)malate
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pH 7.8, 28°C, recombinant enzyme
2 - 8
(2R,3S)-3-(4-hydroxybutyl)malate
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pH 7.8, 28°C, recombinant enzyme
2.1
(2R,3S)-3-(4-hydroxybutyl)malate
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pH 7.8, 36°C, recombinant enzyme
0.14
(2R,3S)-3-(4-pentenyl)malic acid
-
pH 7.8, 36°C, recombinant enzyme
3
(2R,3S)-3-(4-pentenyl)malic acid
-
pH 7.8, 28°C, recombinant enzyme
1.5
3-isopropylmalate
-
mutant enzyme L81P, with NAD+ as cosubstrate, at pH 8.0 and 60°C
2.3
3-isopropylmalate
-
mutant enzyme S80A, with NAD+ as cosubstrate, at pH 8.0 and 60°C
4.8
3-isopropylmalate
-
wild type enzyme, with NAD+ as cosubstrate, at pH 8.0 and 60°C
9.4
3-isopropylmalate
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mutant enzyme T71V, with NAD+ as cosubstrate, at pH 8.0 and 60°C
4.8
homoisocitrate
-
mutant enzyme T71V, with NAD+ as cosubstrate, at pH 8.0 and 60°C
6.9
homoisocitrate
-
mutant enzyme S80A, with NAD+ as cosubstrate, at pH 8.0 and 60°C
12
homoisocitrate
-
wild type enzyme, with NADP+ as cosubstrate, at pH 8.0 and 60°C
13
homoisocitrate
-
mutant enzyme L81P, with NAD+ as cosubstrate, at pH 8.0 and 60°C
17
homoisocitrate
-
wild type enzyme, with NAD+ as cosubstrate, at pH 8.0 and 60°C
43
homoisocitrate
-
mutant enzyme L83R, with NAD+ as cosubstrate, at pH 8.0 and 60°C
45
homoisocitrate
-
mutant enzyme I82N, with NAD+ as cosubstrate, at pH 8.0 and 60°C
0.22
isocitrate
-
mutant enzyme T71V, with NAD+ as cosubstrate, at pH 8.0 and 60°C
0.71
isocitrate
-
mutant enzyme S80A, with NAD+ as cosubstrate, at pH 8.0 and 60°C
1
isocitrate
-
mutant enzyme I82N, with NAD+ as cosubstrate, at pH 8.0 and 60°C
1.1
isocitrate
-
mutant enzyme L81P, with NAD+ as cosubstrate, at pH 8.0 and 60°C
5
isocitrate
-
wild type enzyme, with NAD+ as cosubstrate, at pH 8.0 and 60°C
6.6
isocitrate
-
mutant enzyme L83R, with NAD+ as cosubstrate, at pH 8.0 and 60°C
0.099
NAD+
-
wild type enzyme, with D-malate as cosubstrate, at pH 8.0 and 60°C
4.8
NAD+
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wild type enzyme, with 3-isopropylmalate as cosubstrate, at pH 8.0 and 60°C
5
NAD+
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wild type enzyme, with isocitrate as cosubstrate, at pH 8.0 and 60°C
17
NAD+
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wild type enzyme, with homoisocitrate as cosubstrate, at pH 8.0 and 60°C
