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1.1.1.79: glyoxylate reductase (NADP+)

This is an abbreviated version!
For detailed information about glyoxylate reductase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.79

Reaction

D-glycerate
+
NAD(P)+
=
glyoxylate
+
NADPH
+
H+

Synonyms

aac4036, At3g25530, AtGLYR1, AtGLYR2, AtGR1, AtGR2, D-2-hydroxy-acid dehydrogenase, GhrA, glycerate dehydrogenase, glyoxylate reductase, glyoxylate reductase 1, glyoxylate reductase 2, glyoxylate reductase isoform 1, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate/succinic semialdehyde reductase, GLYR1, GLYR2, GOR1, Gor1p, GR/HPR, GR1, GR2, GRHPR, GRHRP, HPR2, HPR3, More, NAD(P)H-dependent GR, NADPH/NADH-dependent glyoxylate/hydroxypyruvate reductases, PfuGRHPR, PhoGRHPR, PtGR, PyaGRHPR, TthGR1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.79 glyoxylate reductase (NADP+)

Source Tissue

Source Tissue on EC 1.1.1.79 - glyoxylate reductase (NADP+)

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
enzyme GRHPR is lost in hepatocellular carcinoma (HCC) and proliferative HCC cells
Manually annotated by BRENDA team
GRHPR is reduced in proliferative Huh7 cells
Manually annotated by BRENDA team
Populus gelrica
-
-
Manually annotated by BRENDA team
additional information
immunohistochemic tissue expression analysis of GRHPR, overview. GRHPR shows a lower expression in tumor tissues than in nontumoral tissues. GRHPR is negatively correlated with Ki-67
Manually annotated by BRENDA team