1.1.1.78: methylglyoxal reductase (NADH)

This is an abbreviated version!
For detailed information about methylglyoxal reductase (NADH), go to the full flat file.

Reaction

Synonyms

D-lactaldehyde dehydrogenase, dehydrogenase, D-lactaldehyde, methylglyoxal reductase, MGR, MGR I, MGR II

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.78 methylglyoxal reductase (NADH)

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Results	in table
3	Activating Compound
1	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
10	Cofactor
14	Inhibitors
6	KM Value [mM]
1	Localization
6	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
3	Pathway
5	pH Optimum
2	pH Range
4	pH Stability
4	Purification (Commentary)
2	Reaction
3	Reaction Type
6	Reference
8	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
20	Substrates and Products (Substrate)
4	Subunits
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
5	Temperature Stability [°C]

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Reference on EC 1.1.1.78 - methylglyoxal reductase (NADH)

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137611

Tran-Din, K.; Gottschalk, G.

Formation of D(-)-1,2-propanediol and D(-)-lactate from glucose by Clostridium sphenoides under phosphate limitation

Arch. Microbiol.

142

87-92

1985

Lacrimispora sphenoides

207968

Ting, S.M.; Miller, O.N.; Sellinger, O.Z.

The metabolism of lactaldehyde: VII. The oxidation of D-lactaldehyde in rat liver

Biochim. Biophys. Acta

407-415

1965

Rattus norvegicus

14323585

207969

Ray, M.; Ray, S.

Purification and partial characterization of a methylglyoxal reductase from goat liver

Biochim. Biophys. Acta

802

119-127

1984

Capra hircus

6386056

207975

Kato, H.; Miyauchi, Y.; Nishimura, T.; Liang, Z.Q.

Purification and partial characterization of NADH-dependent methylglyoxal-reducing enzyme from porcine liver

Agric. Biol. Chem.

2641-2642

1988

Sus scrofa

207976

Saikusa, T.; Rhee, H.; Watanabe, K.; Murata, K.; Kimura, A.

Metabolism of 2-oxoaldehydes in bacteria: purification and characterization of methylglyoxal reductase from Escherichia coli

Agric. Biol. Chem.

1893-1899

1987

Escherichia coli

657418

Chen, C.N.; Porubleva, L.; Shearer, G.; Svrakic, M.; Holden, L.G.; Dover, J.L.; Johnston, M.; Chitnis, P.R.; Kohl, D.H.

Associating protein activities with their genes: rapid identification of a gene encoding a methylglyoxal reductase in the yeast Saccharomyces cerevisiae

Yeast

545-554

2003

Saccharomyces cerevisiae

12722185