1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

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For detailed information about glucose-6-phosphate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

6-phosphoglucose dehydrogenase, beta-D-glucose-6-phosphate; NADP oxidoreductase, beta-D-glucose-6-phosphate;NADP oxido-reductase, D-glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate:NADP oxidoreductase, Entner-Doudoroff enzyme, G-6-PD, G-6-PDH, G-6PD, G6PD, G6PD1, G6PD2, G6PD3, G6PD4, G6PD5, G6PD6, G6PDH, G6PDH-1, G6PDH-2, G6PDH1, G6PDH2, G6PDH3, G6PDH4, G6PDH5, G6PDH6, Glc6PDH, glucose 6-phosphate dehydrogenase, glucose 6-phosphate dehydrogenase (NADP), glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase Zwf, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, GPD, KlZWF1, NADP-dependent glucose 6-phophate dehydrogenase, NADP-glucose-6-phosphate dehydrogenase, P2-G6PDH, PF14_0511, PfGluPho, plastidial glucose 6-phosphate dehydrogenase, VEG11, Vegetative protein 11, Zwf, zwf-1, Zwf-2, Zwf1p, Zwischenferment

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)

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Results	in table
36	Activating Compound
38779	AA Sequence
16	Application
1	CAS Registry Number
26	Cloned(Commentary)
130	Cofactor
7	Crystallization (Commentary)
30698	Disease/ Diagnostics
12	Expression
30	General Information
5	General Stability
48	IC50 Value
265	Inhibitors
22	kcat/KM [mM/s]
81	Ki Value [mM]
210	KM Value [mM]
40	Localization
52	Metals/Ions
103	Molecular Weight [Da]
108	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
574	Organism
13	Pathway
85	PDB ID
64	pH Optimum
12	pH Range
10	pH Stability
9	pI Value
41	Protein Variants
92	Purification (Commentary)
9	Reaction
4	Reaction Type
191	Reference
1	Renatured (Commentary)
128	Source Tissue
94	Specific Activity [micromol/min/mg]
11	Storage Stability
207	Substrates and Products (Substrate)
71	Subunits
256	Synonyms
1	Systematic Name
49	Temperature Optimum [°C]
4	Temperature Range [°C]
29	Temperature Stability [°C]
69	Turnover Number [1/s]

pI Value

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pI Value on EC 1.1.1.49 - glucose-6-phosphate dehydrogenase (NADP+)

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pI VALUE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

4.5

Taenia crassiceps

-

-

689323

4.85

Pisum sativum

-

isoelectric focusing, pH-gradient: 3.5-7.0, three isoforms with pI: 5.5, 5.3 and 4.85

660941

5.3

Pisum sativum

-

isoelectric focusing, pH-gradient: 3.5-7.0, three isoforms with pI: 5.5, 5.3 and 4.85

660941

5.5

Pisum sativum

-

isoelectric focusing, pH-gradient: 3.5-7.0, three isoforms with pI: 5.5, 5.3 and 4.85

660941

5.7

Deinococcus radiophilus

-

isoelectric focusing, pH-range 3-10, G6PDH-2

688308

5.7 - 5.9

Bos taurus

-

isoform G6PD2, isoelectric focusing

741369

6.4

Deinococcus radiophilus

-

isoelectric focusing, pH-range 3-10, G6PDH-1

688308

6.6 - 6.8

Camelus dromedarius

-

isoelectric focusing

740402

7.7 - 7.9

Bos taurus

-

isoform G6PD1, isoelectric focusing

741369