1.1.1.49: glucose-6-phosphate dehydrogenase (NADP+)

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For detailed information about glucose-6-phosphate dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.49

1.1.1.49

erythrocyte

pentose

hemolytic

catalase

malaria

6-phosphogluconate

anemia

dismutase

neonatal

hexokinase

hemoglobin

gsh

malic

newborn

plasmodium

children

haemolysis

glycogen

malate

jaundice

x-linked

sod

falciparum

isocitrate

hyperbilirubinemia

lipogenic

sickle

infant

bilirubin

shunt

mediterranean

endemic

lipogenesis

glucose-6-phosphatase

vivax

phosphofructokinase

transfusion

glutathione-s-transferase

cytochemical

dehydroepiandrosterone

glucokinase

thiobarbituric

hexose

phosphoglucomutase

methemoglobin

thalassemia

hemoglobinopathy

phototherapy

x-chromosome

synthesis

drug development

medicine

industry

beta-thalassemia

Reaction

Synonyms

6-phosphoglucose dehydrogenase, beta-D-glucose-6-phosphate; NADP oxidoreductase, beta-D-glucose-6-phosphate;NADP oxido-reductase, D-glucose 6-phosphate dehydrogenase, D-glucose 6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate: NADP+ oxidoreductase, D-glucose-6-phosphate:NADP oxidoreductase, Entner-Doudoroff enzyme, G-6-PD, G-6-PDH, G-6PD, G6PD, G6PD1, G6PD2, G6PD3, G6PD4, G6PD5, G6PD6, G6PDH, G6PDH-1, G6PDH-2, G6PDH1, G6PDH2, G6PDH3, G6PDH4, G6PDH5, G6PDH6, Glc6PDH, glucose 6-phosphate dehydrogenase, glucose 6-phosphate dehydrogenase (NADP), glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase Zwf, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, GPD, KlZWF1, NADP-dependent glucose 6-phophate dehydrogenase, NADP-glucose-6-phosphate dehydrogenase, P2-G6PDH, PF14_0511, PfGluPho, plastidial glucose 6-phosphate dehydrogenase, VEG11, Vegetative protein 11, Zwf, zwf-1, Zwf-2, Zwf1p, Zwischenferment

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)

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Results	in table
36	Activating Compound
38779	AA Sequence
16	Application
1	CAS Registry Number
26	Cloned(Commentary)
130	Cofactor
7	Crystallization (Commentary)
30698	Disease/ Diagnostics
12	Expression
30	General Information
5	General Stability
48	IC50 Value
265	Inhibitors
22	kcat/KM [mM/s]
81	Ki Value [mM]
210	KM Value [mM]
40	Localization
52	Metals/Ions
103	Molecular Weight [Da]
108	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
574	Organism
13	Pathway
85	PDB ID
64	pH Optimum
12	pH Range
10	pH Stability
9	pI Value
41	Protein Variants
92	Purification (Commentary)
9	Reaction
4	Reaction Type
191	Reference
1	Renatured (Commentary)
128	Source Tissue
94	Specific Activity [micromol/min/mg]
11	Storage Stability
207	Substrates and Products (Substrate)
71	Subunits
256	Synonyms
1	Systematic Name
49	Temperature Optimum [°C]
4	Temperature Range [°C]
29	Temperature Stability [°C]
69	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.49 - glucose-6-phosphate dehydrogenase (NADP+)

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D-glucose 6-phosphate + H2O + NADP+

D-gluconate 6-phosphate + NADPH + H+

36 entries

D-glucose 6-phosphate + NAD(P)+

D-glucono-1,5-lactone 6-phosphate + NAD(P)H

Canis lupus familiaris

key enzyme catalyzing the first step of the pentose phosphate pathway generating NADPH for anabolic metabolsim pathways and protection systems in the liver

655736

D-glucose 6-phosphate + NADP+

6-phospho-D-glucono-1,5-lactone + NADPH + H+

33 entries

D-glucose 6-phosphate + NADP+

D-glucono-1,5-lactone 6-phosphate + NADPH + H+

26 entries

D-glucose 6-phosphate + NADP+ + H2O

D-gluconate 6-phosphate + NADPH + H+

3 entries

additional information

3 entries