1.1.1.431: D-xylose reductase (NADPH)

This is an abbreviated version!
For detailed information about D-xylose reductase (NADPH), go to the full flat file.

Reaction

Synonyms

ALR1, Cb-XR, CbXR, CtXR, D-xylose reductase, D-xylose reductase 1, D-xylose reductase 2, D-xylose reductase 3, DnXR, GRE3, monospecific xylose reductase, More, msXR, NAD(P)H-dependent D-xylose reductase, NAD(P)H-dependent xylose reductase, NADPH dependent D-xylose reductase, NADPH-dependent D-xylose reductase II,III, NADPH-dependent xylose reductase, NADPH-preferring xylose reductase, NRRL3_10868, SsXR, Texr, TrxR, XR1, XR2, XR3, XRTL, XYL1, xylose reductase, xyr8, XyrA, XyrB

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.431 D-xylose reductase (NADPH)

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Results	in table
5	Activating Compound
16	AA Sequence
10	Application
22	Cloned(Commentary)
64	Cofactor
7	Crystallization (Commentary)
6	Expression
33	General Information
2	General Stability
10	IC50 Value
39	Inhibitors
81	kcat/KM [mM/s]
18	Ki Value [mM]
97	KM Value [mM]
1	Localization
4	Metals/Ions
15	Molecular Weight [Da]
44	Natural Substrates/ Products (Substrates)
113	Organism
1	Pathway
23	pH Optimum
3	pH Range
7	pH Stability
6	pI Value
2	Posttranslational Modification
49	Protein Variants
17	Purification (Commentary)
4	Reaction
65	Reference
3	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
170	Substrates and Products (Substrate)
29	Subunits
99	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
4	Temperature Range [°C]
8	Temperature Stability [°C]
75	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

8.4

2-deoxy-D-galactose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

6.8

2-deoxy-D-glucose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

1.4

2-deoxy-D-ribose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

19 - 22

5,6-dideoxy-5,6-difluoro-D-glucofuranose

2 entries

-

14 - 21

5,6-dideoxy-5-fluoro-D-glucofuranose

2 entries

-

14 - 34

5,6-dideoxy-6-fluoro-D-xylo-hexofuranose

2 entries

-

15 - 27

5,6-dideoxy-D-xylo-hexofuranose

2 entries

-

11.2

5-azido-5-deoxy-D-xylofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

12.5 - 18.1

5-deoxy-D-xylofuranose

2 entries

-

15.6 - 20

5-fluoro-5-deoxy-D-xylofuranose

2 entries

-

14 - 19

6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose

2 entries

-

21.2

Butanal

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

6.3 - 13.1

cyclohexanecarboxaldehyde

2 entries

24.3 - 165

D-erythrose

2 entries

420 - 530

D-fructose

3 entries

20.7

D-fucose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

5.9 - 410

D-galactose

6 entries

8.2 - 3190

D-glucose

4 entries

12.2

D-ribose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

2 - 4638

D-xylose

16 entries

24.3

DL-glyceraldehyde

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

15.61 - 1030

L-arabinose

5 entries

18.4

L-Lyxose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

2.39 - 2.68

NADH

2 entries

0.06 - 14.6

NADPH

6 entries

9.2 - 22

oenanthaldehyde

2 entries

-

20.7

pentanal

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

6.9

propionaldehyde

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

0.6

xylitol

[Candida] intermedia

-

pH 7, 25°C

764945

19

5,6-dideoxy-5,6-difluoro-D-glucofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

22

5,6-dideoxy-5,6-difluoro-D-glucofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

14

5,6-dideoxy-5-fluoro-D-glucofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

21

5,6-dideoxy-5-fluoro-D-glucofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

14

5,6-dideoxy-6-fluoro-D-xylo-hexofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

34

5,6-dideoxy-6-fluoro-D-xylo-hexofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

15

5,6-dideoxy-D-xylo-hexofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

27

5,6-dideoxy-D-xylo-hexofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

12.5

5-deoxy-D-xylofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

18.1

5-deoxy-D-xylofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

15.6

5-fluoro-5-deoxy-D-xylofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

20

5-fluoro-5-deoxy-D-xylofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

14

6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose

Saitozyma flava

-

pH 7, 25°C

764095

-

19

6-azido-5,6-dideoxy-5-fluoro-D-glucofuranose

[Candida] intermedia

-

pH 7, 25°C

764095

-

6.3

cyclohexanecarboxaldehyde

Saitozyma flava

-

pH 7, 25°C

764095

13.1

cyclohexanecarboxaldehyde

[Candida] intermedia

-

pH 7, 25°C

764095

24.3

D-erythrose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

165

D-erythrose

Debaryomyces nepalensis

A0A0M4HL56

recombinant His-tagged enzyme, pH 7.0, 45°C

761066

420

D-fructose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

466

D-fructose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

530

D-fructose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

5.9

D-galactose

Saitozyma flava

-

pH 7, 25°C

764095

9.4

D-galactose

[Candida] intermedia

-

pH 7, 25°C

764095

15.2

D-galactose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

350

D-galactose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

360

D-galactose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

410

D-galactose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

8.2

D-glucose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

790

D-glucose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

1920

D-glucose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

3190

D-glucose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

2 - 8

D-xylose

[Candida] intermedia

-

pH 7, 25°C

764945

3.02

D-xylose

Scheffersomyces stipitis

P31867

with NADH, with 150 mM NaCl, pH 8.0, 30°C

762450

4.34

D-xylose

Scheffersomyces stipitis

P31867

with NADH, without NaCl, pH 8.0, 30°C

762450

6.69

D-xylose

Scheffersomyces stipitis

P31867

with NADPH, with 150 mM NaCl, pH 8.0, 30°C

762450

8.37

D-xylose

Scheffersomyces stipitis

P31867

with NADPH, without NaCl, pH 8.0, 30°C

762450

8.8

D-xylose

Saitozyma flava

-

pH 7, 25°C

764095

9.65

D-xylose

Aspergillus niger

-

recombinant enzyme, pH 7.0, 25°C

760777

13.1

D-xylose

Saccharomyces cerevisiae

-

pH 7.0, 22°C, wild-type enzyme

701424

14.6

D-xylose

[Candida] intermedia

-

pH 7, 25°C

764095, 765140

21.3

D-xylose

Rhizomucor pusillus

I7HD84

pH 7.0, 30°C

740777

23.5

D-xylose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

157

D-xylose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

194.3

D-xylose

Thermomyces lanuginosus

A0A455KZK8

recombinant enzyme, pH 6.5, 50°C

760720

227

D-xylose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

343

D-xylose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

4638

D-xylose

Neurospora crassa

-

pH 6.3, 25°C

696376

15.61

L-arabinose

Aspergillus niger

-

recombinant enzyme, pH 7.0, 25°C

760777

24.5

L-arabinose

[Candida] intermedia

-

pH 7.0, 25°C, NADPH-dependent monospecific xylose reductase, cofactor: NADPH

764945

900

L-arabinose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

1000

L-arabinose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

1030

L-arabinose

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

2.39

NADH

Scheffersomyces stipitis

P31867

with 150 mM NaCl, pH 8.0, 30°C

762450

2.68

NADH

Scheffersomyces stipitis

P31867

without NaCl, pH 8.0, 30°C

762450

0.06

NADPH

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant wild-type enzyme

761007

0.14

NADPH

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered XR-GPI enzyme

761007

0.17

NADPH

Saccharomyces cerevisiae

P38715

pH 5.0, 30°C, recombinant engineered Pir-XR enzyme

761007

7.63

NADPH

Scheffersomyces stipitis

P31867

with 150 mM NaCl, pH 8.0, 30°C

762450

7.65

NADPH

Scheffersomyces stipitis

P31867

without NaCl, pH 8.0, 30°C

762450

14.6

NADPH

[Candida] intermedia

-

pH 7, 25°C

765140

9.2

oenanthaldehyde

Saitozyma flava

-

pH 7, 25°C

764095

-

22

oenanthaldehyde

[Candida] intermedia

-

pH 7, 25°C

764095

-