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1.1.1.430: D-xylose reductase (NADH)

This is an abbreviated version!
For detailed information about D-xylose reductase (NADH), go to the full flat file.

Reaction

xylitol
+
NAD(P)+
=
D-xylose
 +
NAD(P)H
 +
H+

Synonyms

CbXR, CT-XR, dsXR, NAD(P)H-dependent D-xylose reductase, NADH-dependent XR, NADPH-preferring xylose reductase, PsXR, XYL1, XYL1.1, XYL1.2, xylose reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.430 D-xylose reductase (NADH)

Cloned

Cloned on EC 1.1.1.430 - D-xylose reductase (NADH)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
construction of Kluyveromyces marxianus strains expressing Pichia stipitis Psxyl1 genes leading to reversed cofactor specificity and ethanol and xylitol production
-
expression in Candida tropicalis increases production of ethanol and glycerol
expression of His-tagged enzyme in Escherichia coli
-
gene XYL1.1, recombinant expression in Aureobasidium pullulans strain CBS 110374
gene XYL1.2, recombinant expression in Aureobasidium pullulans strain CBS 110374
overexpression of wild-type enzyme and mutant enzyme, with modified cofactor specificity, in Saccharomyces cerevisiae strain CEN.PK 113-7D under control of the constitutive TDH3 promoter, coexpression with xylitol dehydrogenase from Galactocandida mastotermitis, The strain harboring the xylose reductase double mutant shows 42% enhanced ethanol yield compared to the reference strain harboring wild-type xylose reductase during anaerobic bioreactor conversions of xylose. Likewise, the yields of xylitol and glycerol are decreased by 52% and 57% respectively in the xylose reductase mutant strain
-
recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)