1.1.1.428: 4-methylthio 2-oxobutanoate reductase (NADH)

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For detailed information about 4-methylthio 2-oxobutanoate reductase (NADH), go to the full flat file.

Reaction

Synonyms

4-methylthio 2-oxobutyrate reductase, 4-methylthio 2-oxobutyric acid reductase, C-terminal binding protein 1, C-terminal-binding protein 1, C-terminal-binding protein 2, CtBP, CTBP1, CtBP2, MTOB reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.428 4-methylthio 2-oxobutanoate reductase (NADH)

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
6	Cofactor
4	Crystallization (Commentary)
18	IC50 Value
29	Inhibitors
11	kcat/KM [mM/s]
3	Natural Substrates/ Products (Substrates)
6	Organism
1	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
2	Source Tissue
15	Substrates and Products (Substrate)
1	Subunits
17	Synonyms
1	Systematic Name

Purification

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Purification on EC 1.1.1.428 - 4-methylthio 2-oxobutanoate reductase (NADH)

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

Ni-affinity column chromatography

Homo sapiens

-

765380

Ni-NTA column chromatography and Superdex 75 gel filtration

Homo sapiens

P56545, Q13363

764664