1.1.1.418: plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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For detailed information about plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating), go to the full flat file.

Reaction

a 3beta-hydroxysteroid-4alpha-carboxylate

Synonyms

3beta-HSD/D1, 3beta-HSD/D2, 3beta-hydroxysteroid dehydrogenase/C-4 decarboxylase, 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylase, 3beta-hydroxysteroid-dehydrogenase/C4-decarboxylase, 3betaHSD/D, 3betaHSD/D1, 3betaHSD/D2, 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase, 4alpha-CD

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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2	AA Sequence
2	Cloned(Commentary)
3	Cofactor
1	General Stability
16	KM Value [mM]
2	Localization
2	Natural Substrates/ Products (Substrates)
4	Organism
8	Pathway
12	Protein Variants
1	Purification (Commentary)
1	Reaction
3	Reference
18	Substrates and Products (Substrate)
2	Subunits
11	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.1.1.418 - plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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3beta-hydroxysteroid-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating)

The enzyme, found in plants, catalyses multiple reactions during plant sterol biosynthesis. Unlike the fungal/animal enzyme EC 1.1.1.170, 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating), the plant enzyme is specific for NAD+.