1.1.1.413: A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

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For detailed information about A-factor type gamma-butyrolactone 1'-reductase (1S-forming), go to the full flat file.

Reaction

a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one

a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one

Synonyms

BARS1, Virginiae butanolide-specific dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

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Results	in table
16	AA Sequence
1	Cloned(Commentary)
2	Cofactor
1	KM Value [mM]
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
3	Organism
1	Pathway
1	pH Optimum
1	Reaction
3	Reference
14	Substrates and Products (Substrate)
4	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

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Reference on EC 1.1.1.413 - A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

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741791

Lee, Y.J.; Kitani, S.; Kinoshita, H.; Nihira, T.

Identification by gene deletion analysis of barS2, a gene involved in the biosynthesis of gamma-butyrolactone autoregulator in Streptomyces virginiae

Arch. Microbiol.

189

367-374

2008

Streptomyces virginiae

18034227

742772

Shikura, N.; Yamamura, J.; Nihira, T.

barS1, a gene for biosynthesis of a gamma-butyrolactone autoregulator, a microbial signaling molecule eliciting antibiotic production in Streptomyces species

J. Bacteriol.

184

5151-5157

2002

Streptomyces virginiae, Streptomyces virginiae MAFF 10-06014

12193632