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1.1.1.41: isocitrate dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about isocitrate dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.1.1.41

Reaction

isocitrate
+
NAD+
=
2-oxoglutarate
 +
CO2
 +
NADH
 +
H+

Synonyms

At2g17130, At4g35260, At4g35650, At5g03290, AtIDH I, AtIDH II, AtIDH V, AtIDH VI, beta-decarboxylating dehydrogenase, beta-ketoglutaric-isocitric carboxylase, CaIDH, CcIDH, hNAD-IDHalpha, homodimeric NAD+-linked isocitrate dehydrogenase, Icd-2, ICDH, ICDH1, IDH, IDH I, IDH II, IDH III, IDH IV, IDH V, IDH-50, IDH-I, IDH-II, IDH-V, IDH1, IDH2, IDH3, IDH3A, IDH3alpha, IDH5, IDHa, isocitrate dehydrogenase, isocitrate dehydrogenase 2, isocitrate dehydrogenase 3alpha subunit, isocitrate-homoisocitrate dehydrogenase, isocitric acid dehydrogenase, isocitric dehydrogenase, McIDH, mIDH, MiIDH, mitochondrial NAD-dependent isocitrate dehydrogenase, monomeric NAD-IDH, NAD dependent isocitrate dehydrogenase, NAD isocitrate dehydrogenase, NAD isocitric dehydrogenase, NAD(P)+-dependent isocitrate dehydrogenase, NAD+-dependent ICDH, NAD+-dependent IDH, NAD+-dependent isocitrate dehydrogenase, NAD+-dependent isocitrate dehydrogenase 1, NAD+-dependent isocitrate dehydrogenase 3, NAD+-dependent type 1 IDH, NAD+-IDH, NAD+-specific ICDH, NAD+-specific IDH, NAD+-specific isocitrate dehydrogenase, NAD-Dependent IDH, NAD-dependent isocitrate dehydrogenase, NAD-ICDH, NAD-IDH, NAD-isocitrate dehydrogenase, NAD-linked isocitrate dehydrogenase, NAD-specific isocitrate dehydrogenase, NADH-IDH, OlIDH, OtIDH, PF0202, PH1722, Rv0066c, threo-DS-isocitrate:NAD+ oxidoreductase (decarboxylating), type 1 isocitrate dehydrogenase, type II homodimeric NAD-IDH, type II NAD+-specific isocitrate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.41 isocitrate dehydrogenase (NAD+)

Molecular Weight

Molecular Weight on EC 1.1.1.41 - isocitrate dehydrogenase (NAD+)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
108000
-
recombinant His6-tagged enzyme, gel filtration
110000
-
gel filtration
123000
-
disulfide bonded form of subunit IDH2, nonreducing PAGE
145000
-
gel filtration
191800
-
gel filtration
224000
-
ultracentrifugation
238000
-
gel filtration
245000
-
sedimentation equilibrium analysis
250000
-
Superose 6 gel filtration
260000
-
dynamic light scattering
290000
-
Superdex 200 gel filtration
300000 - 340000
-
gel filtration
303000
-
sequence calculation
315000
-
about, recombinant wild-type and mutant enzymes, gel filtration
320000
32850
IDH IV, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
335000
338000
-
gel filtration
35910
IDH III, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
36040
IDH VI, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
36200
IDH V, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
36340
-
4 * 36340, the clasp-like domain of McIDH is a likely site for tetramerization, calculated from sequence
36810
IDH II, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
37000
-
2 * 37000, 1 * 39000, 1 * 39000
37500
-
IDH2, SDS-PAGE
37755
38000
38001
38900
IDH I, without the predicted mitochondrial target peptide, calculated from sequence of amino acids
39000
390000
recombinant His6-tagged enzyme, gel filtration and analytical ultracentrifugation
39590
IDH II, with the predicted mitochondrial target peptide, calculated from sequence of amino acids
39630
IDH I, with the predicted mitochondrial target peptide, calculated from sequence of amino acids
39960
IDH III, with the predicted mitochondrial target peptide, calculated from sequence of amino acids
40500
-
alpha8, 8 * 40500, SDS PAGE, ICDH-1 and ICDH-2
40580
IDH VI, with the predicted mitochondrial target peptide, calculated from sequence of amino acids
40620
IDH V, with the predicted mitochondrial target peptide, calculated from sequence of amino acids
41000
-
alphabeta, 1 * 39000 + 1 * 41000, SDS-PAGE
412000
-
gel filtration
44300
2 * 44300, calculated from sequence
45000
46000
-
2 * 46000, recombinant His6-tagged enzyme, SDS-PAGE
52000
-
8 * 52000, SDS-PAGE
70000
74000
-
recombinant His6-tagged enzyme, gel filtration
75500
-
MALDI-TOF mass spectrometry
80000
81000
recombinant His6-tagged enzyme, gel filtration
83181
-
3 * 83181, calculated from amino acid sequence
83600
-
gel filtration
90000
gel filtration and native PAGE
92000
recombinant His6-tagged enzyme, gel filtration
93000
-
about, sequence calculation
97500
-
gel filtration