1.1.1.398: 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase

This is an abbreviated version!
For detailed information about 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase, go to the full flat file.

Reaction

2-(glutathion-S-yl)-2-methylbut-3-en-1-ol
+ 2 NAD+ +
H2O
=
2-(glutathion-S-yl)-2-methylbut-3-enoate
+ 2 NADH + 2 H+

Synonyms

4-hydroxy-3-glutathionyl-3-methylbut-1-ene dehydrogenase, isoH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.398 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.398 - 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-hydroxy-2-glutathionyl-2-methyl-3-butene + NAD+
N-(2-methyl-1-oxobut-3-en-2-yl)-L-gamma-glutamyl-L-cysteinylglycine + NADH + H+
show the reaction diagram
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-
?
2-glutathionyl-2-methyl-3-butenal + NAD+ + H2O
2-glutathionyl-2-methyl-3-butenoic acid + NADH + H+
show the reaction diagram
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?
additional information
?
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no NADH formation is observed when GSH, methanol, ethanol, glycerol, 2-methylbutanol, 3-methyl-butanol, 1-hydroxy-3-methyl-3-butene, or 1,2-dihydroxy-2-methyl-3-butene are used as a substrate. The conjugates of GSH with 1,2-epoxybutane and 1,2-epoxyhexane are also not substrates
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?