1.1.1.391: 3beta-hydroxycholanate 3-dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about 3beta-hydroxycholanate 3-dehydrogenase (NAD+), go to the full flat file.
Reaction
Synonyms
3beta-HSD, 3beta-HSDH, 3beta-hydroxysteroid dehydrogenase, bile acid 3beta-HSD, iso bile acid dehydrogenase, NAD-dependent 3beta-hydroxysteroid dehydrogenase
ECTree
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General Information
General Information on EC 1.1.1.391 - 3beta-hydroxycholanate 3-dehydrogenase (NAD+)
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metabolism
physiological function
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epimerization of the 3beta-hydroxy to a 3alpha-hydroxy group of epi-bile acids catalyzed by 3beta-hydroxysteroid dehydrogenases and 3-oxo-reductases with 3-dehydro (oxo) bile acids as intermediate products
metabolism
the enzyme is involved in the biosynthetic pathway for the second most abundant class in the gut, 3beta-hydroxy(iso)bile acids
metabolism
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the enzyme is involved in the biosynthetic pathway for the second most abundant class in the gut, 3beta-hydroxy(iso)bile acids
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the iso-bile acid pathway detoxifies deoxycholic acid and thus favors the growth of the keystone genus Bacteroides
physiological function
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the iso-bile acid pathway detoxifies deoxycholic acid and thus favors the growth of the keystone genus Bacteroides
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