1.1.1.363: glucose-6-phosphate dehydrogenase [NAD(P)+]
This is an abbreviated version!
For detailed information about glucose-6-phosphate dehydrogenase [NAD(P)+], go to the full flat file.
Word Map on EC 1.1.1.363
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1.1.1.363
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citrate
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mesenteroides
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leuconostoc
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clarias
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batrachus
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4-hydroxy-2-nonenal
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freshwater
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multicatalytic
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catfish
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hne
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hne-treated
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lipogenic
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8-anilino-1-naphthalenesulfonic
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actinomycin
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pentose
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disease-related
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teleost
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synthesis
- 1.1.1.363
- citrate
- mesenteroides
-
leuconostoc
-
clarias
- batrachus
- 4-hydroxy-2-nonenal
-
freshwater
-
multicatalytic
- catfish
- hne
-
hne-treated
-
lipogenic
-
8-anilino-1-naphthalenesulfonic
- actinomycin
- pentose
-
disease-related
-
teleost
- synthesis
Reaction
Synonyms
G6-PDH, G6PD, G6PDH, G6PDH-1, Glc6PD, Glu-6-PDH, glucose 6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase Zwf, NADP+- and NAD+-dependent G6PDH, PputG6PDH-1, zwf-1
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.1.1.363 - glucose-6-phosphate dehydrogenase [NAD(P)+]
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REACTION DIAGRAM
D-ribulose 5-phosphate + CO2 + NADH + H+
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6-phospho-D-gluconate + NAD+
D-ribulose 5-phosphate + CO2 + NADH + H+
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D-ribulose 5-phosphate + CO2 + NADPH + H+
the enzyme generates NADPH, an essential cofactor for several biosynthetic pathways and antioxidant enzymes
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6-phospho-D-gluconate + NADP+
D-ribulose 5-phosphate + CO2 + NADPH + H+
the enzyme generates NADPH, an essential cofactor for several biosynthetic pathways and antioxidant enzymes
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6-phospho-D-glucono-1,5-lactone + NADH + H+
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D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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?
D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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r
D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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?
D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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r
D-glucose 6-phosphate + NAD+
6-phospho-D-glucono-1,5-lactone + NADH + H+
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6-phospho-D-glucono-1,5-lactone + NADPH + H+
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D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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r
D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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?
D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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r
D-glucose 6-phosphate + NADP+
6-phospho-D-glucono-1,5-lactone + NADPH + H+
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the reaction catalyzed by PputG6PDH-1 yields around 1/3 mol of NADPH and 2/3 mol of NADH per mol of oxidized glucose 6-phosphate, calculation of in vivo relative production of NADH and NADPH during the oxidation of glucose-6-phosphate. The reaction catalyzes by the 6-phosphogluconate dehydrogenase is active during growth on glucose, and it produces NADPH and NADH. In comparison, for the enzyme of Escherichia coli EcG6PDH, the relative production of NADH over NADPH is 1000times lower than for PputG6PDH-1
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additional information
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the reaction catalyzed by PputG6PDH-1 yields around 1/3 mol of NADPH and 2/3 mol of NADH per mol of oxidized glucose 6-phosphate, calculation of in vivo relative production of NADH and NADPH during the oxidation of glucose-6-phosphate. The reaction catalyzes by the 6-phosphogluconate dehydrogenase is active during growth on glucose, and it produces NADPH and NADH. In comparison, for the enzyme of Escherichia coli EcG6PDH, the relative production of NADH over NADPH is 1000times lower than for PputG6PDH-1
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