1.1.1.360: glucose/galactose 1-dehydrogenase

This is an abbreviated version!
For detailed information about glucose/galactose 1-dehydrogenase, go to the full flat file.

Reaction

D-galactopyranose
+
NADP+
=
D-galactono-1,5-lactone
+
NADPH
+
H+

Synonyms

dual-specific glucose/galactose dehydrogenase, GdhA, GlcDH, glucose (galactose) dehydrogenase, glucose/galactose dehydrogenase, TvGlcD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.360 glucose/galactose 1-dehydrogenase

Systematic Name

Systematic Name on EC 1.1.1.360 - glucose/galactose 1-dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
D-glucose/D-galactose 1-dehydrogenase (NADPH)
A zinc protein. The enzyme from the archaeon Picrophilus torridus is involved in glucose and galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway. It shows 20-fold higher activity with NADP+ compared to NAD+. The oxidation of D-glucose and D-galactose is catalysed at a comparable rate (cf. EC 1.1.1.119, glucose 1-dehydrogenase (NADP+) and EC 1.1.1.120, galactose 1-dehydrogenase (NADP+)).