1.1.1.358: 2-dehydropantolactone reductase

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase, go to the full flat file.

Word Map on EC 1.1.1.358

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

conjugated polyketone reductase, conjugated polyketone reductase C2, CPR-C1, CPR-C2, ketopantoyl-lactone reductase, NADPH-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.358 2-dehydropantolactone reductase

Substrates Products

Substrates Products on EC 1.1.1.358 - 2-dehydropantolactone reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methylisatin + NADPH + H+
?
show the reaction diagram
-
86% of the activity compared to isatin
-
0
?
2-dehydropantolactone + NADPH + H+
(R)-pantolactone + NADP+
show the reaction diagram
5-methylisatin + NADPH + H+
?
show the reaction diagram
-
108% of the activity compared to isatin
-
0
?
camphorquinone + NADPH + H+
?
show the reaction diagram
-
97% of the activity compared to isatin
-
0
?
isatin + NADPH + H+
?
show the reaction diagram
-
-
-
0
?