1.1.1.358: 2-dehydropantolactone reductase

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase, go to the full flat file.

Word Map on EC 1.1.1.358

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

conjugated polyketone reductase, conjugated polyketone reductase C2, CPR-C1, CPR-C2, ketopantoyl-lactone reductase, NADPH-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.358 2-dehydropantolactone reductase

KI Value

KI Value on EC 1.1.1.358 - 2-dehydropantolactone reductase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.19
2-dehydropantolactone
-
pH 7.0, 30°C, substrate: isatin
0.0014
3,4-Dihydroxy-3-cyclobutene-1,2-dione
-
pH 7.0, 30°C, substrate: isatin
0.0002
cyclohexenediol-1,2,3,4-tetraone
-
pH 7.0, 30°C, substrate: isatin
3.14
parabanic acid
-
pH 7.0, 30°C, substrate: isatin