1.1.1.358: 2-dehydropantolactone reductase

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase, go to the full flat file.

Word Map on EC 1.1.1.358

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

conjugated polyketone reductase, conjugated polyketone reductase C2, CPR-C1, CPR-C2, ketopantoyl-lactone reductase, NADPH-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.358 2-dehydropantolactone reductase

Crystallization

Crystallization on EC 1.1.1.358 - 2-dehydropantolactone reductase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
apoenzyme and in complex with NADPH, sitting drop vapor diffusion method, using 0.1 M Tris–HCl (pH 8.1) and 23% (w/v) polyethylene glycol 3350, at 20°C
sitting drop vapor diffusion method, using 0.1 M Tris-HCl (pH 8.5), 25% (w/v) PEG3350, and 0.2 M NaCl
sitting drop vapor diffusion method, using 0.1 M Tris-HCl pH 8.1 and 23% (w/v) PEG 3350