Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.326: zerumbone synthase

This is an abbreviated version!
For detailed information about zerumbone synthase, go to the full flat file.

Reaction

10-hydroxy-alpha-humulene
+
NAD+
=
zerumbone
+
NADH
+
H+

Synonyms

ZSD1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.326 zerumbone synthase

Engineering

Engineering on EC 1.1.1.326 - zerumbone synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
K159A
site-directed mutagenesis, inactive mutant
S114A
site-directed mutagenesis, the mutation of Ser144 to Ala enhances the catalytic efficiency of ZSD1 to 10-hydroxy-alpha-humulene compared to wild-type
S142A
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
S144A
site-directed mutagenesis, the mutant shows increased activity compared to the wild-type enzyme
Y155A
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
additional information