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1.1.1.325: sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

This is an abbreviated version!
For detailed information about sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming), go to the full flat file.

Reaction

L-threo-7,8-dihydrobiopterin
+
NADP+
=
sepiapterin
+
NADPH
+
H+

Synonyms

MDSPR, sepiapterin reductase, SPR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

Cloned

Cloned on EC 1.1.1.325 - sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
expression of His-tagged wild-type and selenomethionine-substituted enzymes in Escherichia coli strain BL21(DE3)
-
subtractive cDNA library screening, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic tree, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)