1.1.1.317: perakine reductase

This is an abbreviated version!
For detailed information about perakine reductase, go to the full flat file.

Reaction

raucaffrinoline
+
NADP+
=
perakine
+
NADPH
+
H+

Synonyms

AKR13D1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.317 perakine reductase

Reference

Reference on EC 1.1.1.317 - perakine reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rosenthal, C.; Mueller, U.; Panjikar, S.; Sun, L.; Ruppert, M.; Zhao, Y.; Stöckigt, J.
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants
Acta Crystallogr. Sect. F
62
1286-1289
2006
Rauvolfia serpentina (Q3L181)
Manually annotated by BRENDA team
Sun, L.; Ruppert, M.; Sheludko, Y.; Warzecha, H.; Zhao, Y.; Stöckigt, J.
Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia
Plant Mol. Biol.
67
455-467
2008
Rauvolfia serpentina (Q3L181), Rauvolfia serpentina
Manually annotated by BRENDA team
Sun, L.; Chen, Y.; Rajendran, C.; Mueller, U.; Panjikar, S.; Wang, M.; Mindnich, R.; Rosenthal, C.; Penning, T.M.; Stoeckigt, J.
Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding
J. Biol. Chem.
287
11213-11221
2012
Rauvolfia serpentina (Q3L181)
Manually annotated by BRENDA team