1.1.1.307: D-xylose reductase [NAD(P)H]
This is an abbreviated version!
For detailed information about D-xylose reductase [NAD(P)H], go to the full flat file.
Word Map on EC 1.1.1.307
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1.1.1.307
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synthesis
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l-arabinose
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stipitis
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kluyveromyces
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marxianus
-
oxygen-limited
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nadph-linked
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reesei
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l-arabitol
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trichoderma
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passalidarum
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scheffersomyces
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spathaspora
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jecorina
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pachysolen
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pentitols
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bioethanol
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hypocrea
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tannophilus
-
galactitol
- 1.1.1.307
- synthesis
- l-arabinose
- stipitis
-
kluyveromyces
- marxianus
-
oxygen-limited
-
nadph-linked
- reesei
- l-arabitol
- trichoderma
- passalidarum
-
scheffersomyces
- spathaspora
- jecorina
-
pachysolen
- pentitols
-
bioethanol
- hypocrea
- tannophilus
- galactitol
Reaction
Synonyms
AKR2B5, ALR2, CTHT_0056950, CtXR, dsXR, dual specific xylose reductase, KmXYL1, NAD(P)H-dependent D-xylose reductase, NAD(P)H-dependent D-xylose reductase-like protein, NAD(P)H-dependent XR, NAD(P)H-dependent xylose reductase, NAD(P)H-linked xylose reductase, NADH/NADPH-xylose reductase, NADP-dependent xylose reductase, PsXR, PsXYL1, SaXYL1, SpXYL1.1, SsXR, Texr, XR, XYL1, xylose reductase, XylR, XyrA
ECTree
1.1.1.307 D-xylose reductase [NAD(P)H]Advanced search results
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Reference on EC 1.1.1.307 - D-xylose reductase [NAD(P)H]
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Neuhauser, W.; Haltrich, D.; Kulbe, K.D.; Nidetzky, B.
NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis
Biochem. J.
326
683-692
1997
Yamadazyma tenuis
Woodyer, R.; Simurdiak, M.; van der Donk, W.A.; Zhao, H.
Heterologous expression, purification, and characterization of a highly active xylose reductase from Neurospora crassa
Appl. Environ. Microbiol.
71
1642-1647
2005
Neurospora crassa
Sasaki, M.; Jojima, T.; Inui, M.; Yukawa, H.
Xylitol production by recombinant Corynebacterium glutamicum under oxygen deprivation
Appl. Microbiol. Biotechnol.
86
1057-1066
2009
Yamadazyma tenuis
Verduyn, C.; van Kleef, R.; Frank, J.; Schreuder, H.; van Dijken, J.P.; Scheffers, W.A.
Properties of the NAD(P)H-dependent xylose reductase from the xylose-fermenting yeast Pichia stipitis
Biochem. J.
226
669-677
1985
Scheffersomyces stipitis
Häcker, B.; Habenicht, A.; Kiess, M.; Mattes, R.
Xylose utilisation: cloning and characterisation of the xylose reductase from Candida tenuis
Biol. Chem.
380
1395-1403
1999
Yamadazyma tenuis (O74237), Yamadazyma tenuis CBS 4435 (O74237)
Bengtsson, O.; Hahn-Hägerdal, B.; Gorwa-Grauslund, M.F.
Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae
Biotechnol. Biofuels
2
904-912
2009
Scheffersomyces stipitis
Fernandes, S.; Tuohy, M.G.; Murray, P.G.
Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (TexrK271R + N273D) with altered coenzyme specificity
J. Biosci.
34
881-890
2009
Rasamsonia emersonii (C5J3R6)
Gurpilhares, D.B.; Hasmann, F.A.; Pessoa, A.; Roberto, I.C.
The behavior of key enzymes of xylose metabolism on the xylitol production by Candida guilliermondii grown in hemicellulosic hydrolysate
J. Ind. Microbiol. Biotechnol.
36
87-93
2009
Meyerozyma guilliermondii
Zhang, F.; Qiao, D.; Xu, H.; Liao, C.; Li, S.; Cao, Y.
Cloning, expression, and characterization of xylose reductase with higher activity from Candida tropicalis
J. Microbiol.
47
351-357
2009
Candida tropicalis (A9QVV8), Candida tropicalis SCTCC 300249 (A9QVV8)
Liang, L.; Zhang, J.; Lin, Z.
Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing
Microb. Cell Fact.
6
36
2007
Scheffersomyces stipitis
Zeng, Q.K.; Du, H.L.; Wang, J.F.; Wei, D.Q.; Wang, X.N.; Li, Y.X.; Lin, Y.
Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis
Biotechnol. Lett.
31
1025-1029
2009
Scheffersomyces stipitis (P31867)
Runquist, D.; Hahn-Haegerdal, B.; Bettiga, M.
Increased ethanol productivity in xylose-utilizing Saccharomyces cerevisiae via a randomly mutagenized xylose reductase
Appl. Environ. Microbiol.
76
7796-7802
2010
Saccharomyces cerevisiae, Saccharomyces cerevisiae TMB 3420
Jeon, W.Y.; Yoon, B.H.; Ko, B.S.; Shim, W.Y.; Kim, J.H.
Xylitol production is increased by expression of codon-optimized Neurospora crassa xylose reductase gene in Candida tropicalis
Bioprocess Biosyst. Eng.
35
191-198
2012
Candida tropicalis, Candida tropicalis ATCC 20336
Krahulec, S.; Klimacek, M.; Nidetzky, B.
Analysis and prediction of the physiological effects of altered coenzyme specificity in xylose reductase and xylitol dehydrogenase during xylose fermentation by Saccharomyces cerevisiae
J. Biotechnol.
158
192-202
2012
Saccharomyces cerevisiae
Bolotnikova, O.; Meshcheryakova, O.; Mikhailova, N.; Ginak, A.
Metabolic properties of Pachysolen tannophilus mutants producing xylitol and ethanol from D-xylose
Microbiology
84
485-490
2015
Pachysolen tannophilus, Pachysolen tannophilus 22-Y-1532
-
Zhang, C.; Zong, H.; Zhuge, B.; Lu, X.; Fang, H.; Zhuge, J.
Production of xylitol from D-xylose by overexpression of xylose reductase in osmotolerant yeast Candida glycerinogenes WL2002-5
Appl. Biochem. Biotechnol.
176
1511-1527
2015
Scheffersomyces stipitis
Kim, J.S.; Park, J.B.; Jang, S.W.; Ha, S.J.
Enhanced xylitol production by mutant Kluyveromyces marxianus 36907-FMEL1 due to improved xylose reductase activity
Appl. Biochem. Biotechnol.
176
1975-1984
2015
Kluyveromyces marxianus (A0A0H3Y829), Kluyveromyces marxianus, Kluyveromyces marxianus ATCC 36907 (A0A0H3Y829), Kluyveromyces marxianus ATCC 36907
Zheng, Y.; Yu, X.; Li, T.; Xiong, X.; Chen, S.
Induction of D-xylose uptake and expression of NAD(P)H-linked xylose reductase and NADP+-linked xylitol dehydrogenase in the oleaginous microalga Chlorella sorokiniana
Biotechnol. Biofuels
7
125
2014
Chlorella sorokiniana, Chlorella sorokiniana UTEX 1602
Tani, T.; Taguchi, H.; Akamatsu, T.
Analysis of metabolisms and transports of xylitol using xylose- and xylitol-assimilating Saccharomyces cerevisiae
J. Biosci. Bioeng.
123
613-620
2017
Scheffersomyces stipitis (P31867), Scheffersomyces stipitis NRRL Y-11545 (P31867), Scheffersomyces stipitis NBRC 10063 (P31867), Scheffersomyces stipitis ATCC 58785 (P31867)
Park, J.B.; Kim, J.S.; Kweon, D.H.; Kweon, D.H.; Seo, J.H.; Ha, S.J.
Overexpression of endogenous xylose reductase enhanced xylitol productivity at 40°C by thermotolerant yeast Kluyveromyces marxianus
Appl. Biochem. Biotechnol.
189
459-470
2019
Kluyveromyces marxianus (W0T4K1), Kluyveromyces marxianus, Kluyveromyces marxianus NBRC 104275 (W0T4K1), Kluyveromyces marxianus BCC 29191 (W0T4K1), Kluyveromyces marxianus DMKU3-1042 (W0T4K1)
Jo, J.H.; Park, Y.C.; Jin, Y.S.; Seo, J.H.
Construction of efficient xylose-fermenting Saccharomyces cerevisiae through a synthetic isozyme system of xylose reductase from Scheffersomyces stipitis
Biores. Technol.
241
88-94
2017
Scheffersomyces stipitis (P31867), Scheffersomyces stipitis NRRL Y-11545 (P31867), Scheffersomyces stipitis NBRC 10063 (P31867), Scheffersomyces stipitis ATCC 58785 (P31867)
Jin, L.Q.; Yang, B.; Xu, W.; Chen, X.X.; Jia, D.X.; Liu, Z.Q.; Zheng, Y.G.
Immobilization of recombinant Escherichia coli whole cells harboring xylose reductase and glucose dehydrogenase for xylitol production from xylose mother liquor
Biores. Technol.
285
121344
2019
Rhizopus arrhizus (W5RZ21)
Guirimand, G.G.Y.; Bamba, T.; Matsuda, M.; Inokuma, K.; Morita, K.; Kitada, Y.; Kobayashi, Y.; Yukawa, T.; Sasaki, K.; Ogino, C.; Hasunuma, T.; Kondo, A.
Combined cell surface display of beta-D-glucosidase (BGL), maltose transporter (MAL11), and overexpression of cytosolic xylose reductase (XR) in Saccharomyces cerevisiae enhance cellobiose/xylose coutilization for xylitol bioproduction from lignocellulosic B
Biotechnol. J.
14
e1800704
2019
Scheffersomyces stipitis (P31867), Scheffersomyces stipitis NRRL Y-11545 (P31867), Scheffersomyces stipitis NBRC 10063 (P31867), Scheffersomyces stipitis ATCC 58785 (P31867)
Kim, H.; Lee, H.S.; Park, H.; Lee, D.H.; Boles, E.; Chung, D.; Park, Y.C.
Enhanced production of xylitol from xylose by expression of Bacillus subtilis arabinose H+ symporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae
Enzyme Microb. Technol.
107
7-14
2017
Scheffersomyces stipitis (P31867), Scheffersomyces stipitis NRRL Y-11545 (P31867), Scheffersomyces stipitis NBRC 10063 (P31867), Scheffersomyces stipitis ATCC 58785 (P31867)
Mouro, A.; Santos, A.; Agnolo, D.; Gubert, G.; Bon, E.; Rosa, C.; Fonseca, C.; Stambuk, B.
Combining xylose reductase from Spathaspora arborariae with xylitol dehydrogenase from Spathaspora passalidarum to promote xylose consumption and fermentation into xylitol by Saccharomyces cerevisiae
Fermentation
6
72
2020
Spathaspora arborariae, Spathaspora arborariae UFMG-HM.19.1AT
-
Quehenberger, J.; Reichenbach, T.; Baumann, N.; Rettenbacher, L.; Divne, C.; Spadiut, O.
Kinetics and predicted structure of a novel xylose reductase from Chaetomium thermophilum
Int. J. Mol. Sci.
20
185
2019
Thermochaetoides thermophila (G0SCE7), Thermochaetoides thermophila IMI 039719 (G0SCE7), Thermochaetoides thermophila DSM 1495 (G0SCE7), Thermochaetoides thermophila CBS 144.50 (G0SCE7)
Louie, T.M.; Louie, K.; DenHartog, S.; Gopishetty, S.; Subramanian, M.; Arnold, M.; Das, S.
Production of bio-xylitol from D-xylose by an engineered Pichia pastoris expressing a recombinant xylose reductase did not require any auxiliary substrate as electron donor
Microb. Cell Fact.
20
50
2021
Scheffersomyces stipitis (P31867), Neurospora crassa (Q7SD67), Neurospora crassa CBS 708.71 (Q7SD67), Neurospora crassa 74-OR23-1A (Q7SD67), Scheffersomyces stipitis NRRL Y-11545 (P31867), Scheffersomyces stipitis NBRC 10063 (P31867), Neurospora crassa DSM 1257 (Q7SD67), Neurospora crassa ATCC 24698 (Q7SD67), Scheffersomyces stipitis ATCC 58785 (P31867), Neurospora crassa FGSC 987 (Q7SD67)
Malla, S.; Gummadi, S.N.
Simultaneous optimization of activity and stability of xylose reductase from D. nepalensis NCYC 3413 using statistical experimental design
Protein Pept. Lett.
28
489-500
2020
Debaryomyces nepalensis (A0A0M4HL56), Debaryomyces nepalensis NCYC 3413 (A0A0M4HL56)
Arumugam, N.; Boobalan, T.; Saravanan, S.; Jothi Basu, M.; Arun, A.; Suganya Devi, T.; Kavitha, T.
In silico and in vitro comparison of nicotinamide adenine dinucleotide phosphate dependent xylose reductase Rossmann fold in Debaryomycetaceae yeast family
Biocatal. Agricult. Biotechnol.
24
101508
2020
Meyerozyma caribbica (A0A2Z4P5B1)
-
Nidetzky, B.; Mayr, P.; Hadwiger, P.; Stuetz, A.
Binding energy and specificity in the catalytic mechanism of yeast aldose reductases
Biochem. J.
344
101-107
1999
Yamadazyma tenuis, [Candida] intermedia (A0A1L0DQY1)
Petschacher, B.; Leitgeb, S.; Kavanagh, K.L.; Wilson, D.K.; Nidetzky, B.
The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography
Biochem. J.
385
75-83
2005
Yamadazyma tenuis (O74237)
Nidetzky, B.; Brueggler, K.; Kratzer, R.; Mayr, P.
Multiple forms of xylose reductase in Candida intermedia comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies
J. Agric. Food Chem.
51
7930-7935
2003
[Candida] intermedia
Suzuki, T.; Yokoyama, S.; Kinoshita, Y.; Yamada, H.; Hatsu, M.; Takamizawa, K.; Kawai, K.
Expression of xyrA gene encoding for D-xylose reductase of Candida tropicalis and production of xylitol in Escherichia coli
J. Biosci. Bioeng.
87
280-284
1999
Candida tropicalis (O13283)
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