Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.305: UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)

This is an abbreviated version!
For detailed information about UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating), go to the full flat file.

Reaction

UDP-alpha-D-glucuronate
+
NAD+
=
UDP-beta-L-threo-pentapyranos-4-ulose
+
CO2
+
NADH
+
H+

Synonyms

ArnA, ArnA dehydrogenase, ArnADH, RsU4kpxs, UDP-alpha-D-xylose synthase, UDP-GlcUA dehydrogenase, UGA decarboxylase, UXS

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)

Activating Compound

Activating Compound on EC 1.1.1.305 - UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NAD+
-
exogenous NAD+ stimulates enzyme activity, because a small fraction of hUXS releases the NADH and UDP-alpha-D-4-dehydroxylose intermediates as products during turnover. The resulting apoenzyme can be rescued by exogenous NAD+, explaining the apparent stimulatory effect of added cofactor