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1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

This is an abbreviated version!
For detailed information about 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase, go to the full flat file.

Reaction

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
+
NAD(P)+
=
2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
+
NAD(P)H
+
H+

Synonyms

2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase, 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, arfC, MJ0671, MJ0671 pyrimidine reductase, MjaRED, ribD2

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

Reference

Reference on EC 1.1.1.302 - 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hollander, I.; Brown, G.M.
Biosynthesis of riboflavin: reductase and deaminase of Ashbya gossypii
Biochem. Biophys. Res. Commun.
89
759-763
1979
Eremothecium gossypii
Manually annotated by BRENDA team
Graupner, M.; Xu, H.; White, R.H.
The pyrimidine nucleotide reductase step in riboflavin and F(420) biosynthesis in archaea proceeds by the eukaryotic route to riboflavin
J. Bacteriol.
184
1952-1957
2002
Methanocaldococcus jannaschii, Methanosarcina thermophila
Manually annotated by BRENDA team
Chatwell, L.; Krojer, T.; Fidler, A.; Römisch, W.; Eisenreich, W.; Bacher, A.; Huber, R.; Fischer, M.J.
Biosynthesis of riboflavin: structure and properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase of Methanocaldococcus jannaschii
Mol. Biol.
359
1334-1351
2006
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Römisch-Margl, W.; Eisenreich, W.; Haase, I.; Bacher, A.; Fischer, M.
2,5-Diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthases of fungi and archaea
FEBS J.
275
4403-4414
2008
Aquifex aeolicus (O66747), Methanocaldococcus jannaschii (Q58085), [Candida] glabrata (Q6FU96), Methanocaldococcus jannaschii DSM 2661 (Q58085), [Candida] glabrata ATCC 2001 (Q6FU96)
Manually annotated by BRENDA team