1.1.1.295: momilactone-A synthase

This is an abbreviated version, for detailed information about momilactone-A synthase, go to the full flat file.

Reaction

3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide
+
NAD(P)+
=
momilactone A
+
NAD(P)H
+
H+

Synonyms

3beta-hydroxy-9beta-primara-7,15-dien-19,6beta-olide dehydrogenase, AK103462 protein, MS1, MS2, Os04g0179200, OsMAS

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.295 momilactone-A synthase

Systematic Name

Systematic Name on EC 1.1.1.295 - momilactone-A synthase

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SYSTEMATIC NAME
IUBMB Comments
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide:NAD(P)+ oxidoreductase
The rice phytoalexin momilactone A is a diterpenoid secondary metabolite that is involved in the defense mechanism of the plant. Momilactone A is produced in response to attack by a pathogen through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation. The enzyme, which catalyses the last step in the biosynthesis of momilactone A, can use both NAD+ and NADP+ but activity is higher with NAD+ [1].