1.1.1.290: 4-phosphoerythronate dehydrogenase

This is an abbreviated version!
For detailed information about 4-phosphoerythronate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.290

Reaction

4-phospho-D-erythronate
+
NAD+
=
(3R)-3-hydroxy-2-oxo-4-phosphooxybutanoate
 +
NADH
 +
H+

Synonyms

4-O-phosphoerythronate dehydrogenase, D-erythronate-4-phosphate dehydrogenase, erythronate-4-phosphate dehydrogenase, More, pdx gene product, PDXB, PdxB 4PE dehydrogenase, RdxB

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.290 4-phosphoerythronate dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.290 - 4-phosphoerythronate dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
11
2-oxoglutarate
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C
6700
4-phospho-D-erythronate
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C; pH 8.0, 22°C, recombinant enzyme
13
oxaloacetic acid
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C
9.9
pyruvate
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C