1.1.1.29: glycerate dehydrogenase

This is an abbreviated version!
For detailed information about glycerate dehydrogenase, go to the full flat file.

Reaction

Synonyms

D-glycerate dehydrogenase, dehydrogenase, glycerate, GDH, glyoxalate reductase/hydroxypyruvate reductase, glyoxylate reductase, GR/HPR, GRHPR, HPR, HPR1, hydroxypyruvate dehydrogenase, hydroxypyruvate reductase, hydroxypyruvate reductase 1, NADH-dependent hydroxypyruvate reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.29 glycerate dehydrogenase

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Results	in table
2789	AA Sequence
1	Application
1	CAS Registry Number
1	Cloned(Commentary)
29	Cofactor
33	Disease/ Diagnostics
1	Expression
4	General Information
15	Inhibitors
25	KM Value [mM]
7	Localization
10	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
23	Organism
11	Pathway
2	PDB ID
3	pH Optimum
1	pH Stability
2	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
23	Reference
21	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
27	Substrates and Products (Substrate)
7	Subunits
21	Synonyms
1	Systematic Name
4	Temperature Stability [°C]
12	Turnover Number [1/s]

Disease

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Disease on EC 1.1.1.29 - glycerate dehydrogenase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

glycerate dehydrogenase deficiency

Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II.

12110000

glycerate dehydrogenase deficiency

Reconstruction of human hepatocyte glyoxylate metabolic pathways in stably transformed Chinese-hamster ovary cells.

16309382

Hyperoxaluria

Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II.

12110000

Hyperoxaluria, Primary

Coenzyme specificity of mammalian liver D-glycerate dehydrogenase.

2689175

Hyperoxaluria, Primary

Enzymological characterization of a feline analogue of primary hyperoxaluria type 2: a model for the human disease.

2516173

Hyperoxaluria, Primary

Extraction of glyceric and glycolic acids from urine with tetrahydrofuran: utility in detection of primary hyperoxaluria.

9267307

Hyperoxaluria, Primary

Identification of missense, nonsense, and deletion mutations in the GRHPR gene in patients with primary hyperoxaluria type II (PH2).

11030416

Hyperoxaluria, Primary

Kinetic analysis and tissue distribution of human D-glycerate dehydrogenase/glyoxylate reductase and its relevance to the diagnosis of primary hyperoxaluria type 2.

9463747

Hyperoxaluria, Primary

Oral findings associated with primary hyperoxaluria type I.

22417769

Hyperoxaluria, Primary

Perspectives in the assessment and management of patients with primary hyperoxaluria type I.

2493726

Hyperoxaluria, Primary

Primary hyperoxaluria type 2: enzymology.

9604806

Infections

Enteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression.

32556816

Metabolic Diseases

Restrictive cardiomyopathy in a patient with primary hyperoxaluria type II.

16598594

Urolithiasis

Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II.

12110000

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