1.1.1.286: isocitrate-homoisocitrate dehydrogenase
This is an abbreviated version!
For detailed information about isocitrate-homoisocitrate dehydrogenase, go to the full flat file.
Reaction
Synonyms
3-carboxy-2-hydroxyadipate dehydrogenase, HICDH, homoisocitrate dehydrogenase, isocitrate-homoisocitrate dehydrogenase, More, Saci_2375, TK0280
ECTree
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Metals Ions
Metals Ions on EC 1.1.1.286 - isocitrate-homoisocitrate dehydrogenase
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K+
Mg2+
Mn2+
K+
-
best activator, 200 mM activates by 100%, increases the affinity of enzyme for NAD+ at high pH
-
divalent cation required, Mg2+ is preferred over Mn2+, inhibitory above 1 mM