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1.1.1.265: 3-methylbutanal reductase

This is an abbreviated version!
For detailed information about 3-methylbutanal reductase, go to the full flat file.

Word Map on EC 1.1.1.265

Reaction

3-Methylbutanol
+
NAD(P)+
=
3-Methylbutanal
+
NAD(P)H
+
H+

Synonyms

3-methylbutyraldehyde reductase, aldehyde reductase, bcADH, branched-chain alcohol dehydrogenase, Gre2, GRE2 gene product, Gre2p, isoamylaldehyde reductase, isopentanal reductase, isovaleral reductase, isovaleraldehyde reductase, More, protein YIM1, YIM1, YMR152W, Ymr152wp, YOL151W, YOL151w gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.265 3-methylbutanal reductase

Substrates Products

Substrates Products on EC 1.1.1.265 - 3-methylbutanal reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,3-pentanedione + NAD(P)H
? + NAD(P)+
show the reaction diagram
-
very low activity
-
?
2-methylbutanal + NAD(P)H
2-methylbutanol + NAD(P)+
show the reaction diagram
-
-
-
r
3-methylbutanal + NAD(P)H
3-methylbutanol + NAD(P)+
show the reaction diagram
3-methylbutanal + NAD(P)H + H+
3-methylbutanol + NAD(P)+
show the reaction diagram
-
-
-
r
3-methylbutanal + NADH + H+
3-methylbutanol + NAD+
show the reaction diagram
-
-
-
-
r
3-methylbutanal + NADPH + H+
3-methylbutanol + NADP+
show the reaction diagram
3-methylthiopropionaldehyde + NADPH + H+
3-methylthiopropanol + NADP+
show the reaction diagram
-
specific substrate for Sacchaormyces cerevisiae, main contribution to the strong worty flavor of alcohol-free beer
-
?
3-pyridine carboxaldehyde + NAD(P)H
3-pyridinemethanol + NAD(P)+
show the reaction diagram
-
highest activity
-
?
5-hydroxymethylfurfural + NADH + H+
2,5-dihydroxymethylfurane + NAD+
show the reaction diagram
-
-
-
r
acetaldehyde + NADH + H+
ethanol + NAD+
show the reaction diagram
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
benzaldehyde + NAD(P)H
benzyl alcohol + NAD(P)+
show the reaction diagram
benzaldehyde + NADPH + H+
benzylalcohol + NADP+
show the reaction diagram
butanal + NAD(P)H + H+
butanol + NAD(P)+
show the reaction diagram
-
-
-
r
diacetyl + NAD(P)H
? + NAD(P)+
show the reaction diagram
furaldehyde + NAD(P)H
furfuryl alcohol + NAD(P)+
show the reaction diagram
furfural + NADH + H+
furfuryl alcohol + NAD+
show the reaction diagram
gluconate + NAD(P)H
D-glucose + NAD(P)+
show the reaction diagram
-
very low activity in both reduction and oxidation
-
r
glyceraldehyde + NAD(P)H
glycerol + NAD(P)+
show the reaction diagram
-
-
-
?
glycolaldehyde + NADH + H+
ethylene glycol + NAD+
show the reaction diagram
-
-
-
r
heptanal + NADPH
heptanol + NADP+
show the reaction diagram
-
preference for long and branched-chain substrates with up to seven carbon atoms
-
r
hexanal + NADPH + H+
hexanol + NADP+
show the reaction diagram
isovaleraldehyde + NADPH + H+
isoamyl alcohol + NADP+
show the reaction diagram
-
important role in the suppression of filamentation in response to isoamyl alcohol/isovaleraldehyde
-
-
r
methyl glyoxal + NAD(P)H
? + NAD(P)+
show the reaction diagram
-
low activity
-
?
octanal + NAD(P)H + H+
octanol + NAD(P)+
show the reaction diagram
-
-
-
?
p-anisaldehyde + NAD(P)H
p-anisalcohol + NAD(P)+
show the reaction diagram
-
20-50% of the activity with 3-methylbutanal for aromatic aldehydes
-
?
pentanal + NADPH
pentanol + NADP+
show the reaction diagram
propanal + NAD(P)H + H+
propanol + NAD(P)+
show the reaction diagram
-
-
-
r
trans-2-hexenol + NADP+
trans-2-hexenal + NADPH
show the reaction diagram
-
-
-
?
additional information
?
-