1.1.1.262: 4-hydroxythreonine-4-phosphate dehydrogenase

This is an abbreviated version!
For detailed information about 4-hydroxythreonine-4-phosphate dehydrogenase, go to the full flat file.

Reaction

4-phosphooxy-L-threonine
+
NAD+
=
3-amino-2-oxopropyl phosphate
+
CO2
+
NADH
+
H+

Synonyms

4-(phosphohydroxy)-L-threonine dehydrogenase, L-threonine 4-phosphate dehydrogenase, NAD-dependent threonine 4-phosphate dehydrogenase, PdxA

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase

Reference

Reference on EC 1.1.1.262 - 4-hydroxythreonine-4-phosphate dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Laber, B.; Maurer, W.; Scharf, S.; Stepusin, K.; Schmidt, F.S.
Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein
FEBS Lett.
449
45-48
1999
Escherichia coli
Manually annotated by BRENDA team
Cane, D.E.; Du, S.; Robinson, J.K.; Hsiung, Y.; Spenser, I.D.
Biosynthesis of vitamin B6: enzymatic conversion of 1-deoxy-D-xylulose-5-phosphate to pyridoxol phosphate
J. Am. Chem. Soc.
121
7722-7723
1999
Escherichia coli
-
Manually annotated by BRENDA team
Cane, D.E.; Hsiung, Y.; Cornish, J.A.; Robinson, J.K.; Spenser, I.D.
Biosynthesis of vitamin B6: the oxidation of 4-(phosphohydroxy)-L-threonine by PdxA
J. Am. Chem. Soc.
120
1936-1937
1998
Escherichia coli
-
Manually annotated by BRENDA team
Banks, J.; Cane, D.E.
Biosynthesis of vitamin B6: direct identification of the product of the PdxA-catalyzed oxidation of 4-hydroxy-L-threonine-4-phosphate using electrospray ionization mass spectrometry
Bioorg. Med. Chem. Lett.
14
1633-16367
2004
Escherichia coli
Manually annotated by BRENDA team
Sivaraman, J.; Li, Y.; Banks, J.; Cane, D.E.; Matte, A.; Cygler, M.
Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway
J. Biol. Chem.
278
43682-43690
2003
Escherichia coli (P19624), Escherichia coli
Manually annotated by BRENDA team