1.1.1.243: carveol dehydrogenase

This is an abbreviated version!
For detailed information about carveol dehydrogenase, go to the full flat file.

Reaction

(-)-trans-carveol
+
NADP+
=
(-)-Carvone
+
NADPH
+
H+

Synonyms

(-)-carveol dehydrogenase, A0R518 homolog, Cdh, dehydrogenase, (-)-trans-carveol, MythA.01326.c

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.243 carveol dehydrogenase

Crystallization

Crystallization on EC 1.1.1.243 - carveol dehydrogenase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
to 1.95 A resolution. STD-NMR demonstrates binding of the potential substrate carveol, the potential product carvone, the inhibitor tricyclazol, and external redox partner 2,6-dichloroindophenol. The enzyme appears to contain a non-exchangeable NAD cofactor and may rely on an external redox partner, rather than cofactor exchange, for multiple turnover