1.1.1.23: histidinol dehydrogenase

This is an abbreviated version!
For detailed information about histidinol dehydrogenase, go to the full flat file.

Reaction

Synonyms

11412251, BN980_GECA03s06082g, BsHDH, GcHDH, HDH, HIS4 protein, HisD, histidinol dehydrogenase, HLDase, L-histidinol dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.23 histidinol dehydrogenase

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Results	in table
1	Activating Compound
37903	AA Sequence
14	Application
1	CAS Registry Number
12	Cloned(Commentary)
46	Cofactor
6	Crystallization (Commentary)
51	General Information
95	IC50 Value
145	Inhibitors
6	kcat/KM [mM/s]
5	Ki Value [mM]
38	KM Value [mM]
6	Localization
79	Metals/Ions
23	Molecular Weight [Da]
86	Natural Substrates/ Products (Substrates)
66	Organism
5	Pathway
31	PDB ID
16	pH Optimum
2	pH Range
1	pH Stability
7	Protein Variants
13	Purification (Commentary)
20	Reaction
1	Reaction Type
59	Reference
8	Source Tissue
23	Specific Activity [micromol/min/mg]
3	Storage Stability
132	Substrates and Products (Substrate)
30	Subunits
45	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.1.1.23 - histidinol dehydrogenase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.0003

Cucumis sativus

-

enriched extracts

286329

0.0004

2 entries

0.0009

Asparagus officinalis

-

enriched extracts

286329

0.0016

Brassica oleracea

-

enriched extracts

286329

0.0021

Triticum aestivum

-

enriched extracts

286329

0.0061

Brassica oleracea var. capitata

-

enriched extracts

286329

0.0062

Rosa sp.

-

enriched extracts

286329

1.2

Mycobacterium tuberculosis

P9WNW9

purified recombinant enzyme, pH 7.2, 25°C

721426

10

Brassica oleracea

-

recombinant enzym

286327

10.16

Brassica oleracea

-

-

286329

12.3

Salmonella enterica subsp. enterica serovar Typhimurium

-

oxidation of histidinal

286331

12.5

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

286336

12.71

Escherichia coli

-

-

286336

14.2

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

286331

14.3

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

286339

15.32

Escherichia coli

-

-

286332

3.11

Sporosarcina psychrophila

-

-

286337

3.56

Bacillus subtilis

-

-

286337

3.86

Geobacillus stearothermophilus

-

-

286337

3.89

2 entries

additional information

Bos taurus

-

the activity of the enzyme in different tissues at different pH values, development of a determination method for quantification of L-histidinol and L-histidine using isocratic HPLC, overview

656358

0.0004

Lactuca sativa

-

enriched extracts

286329

0.0004

Solanum melongena

-

enriched extracts

286329

3.89

Bacillus subtilis

-

-

286337

3.89

[Bacillus] caldolyticus

-

-

286337