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1.1.1.23: histidinol dehydrogenase

This is an abbreviated version!
For detailed information about histidinol dehydrogenase, go to the full flat file.

Reaction

L-histidinol
+ 2 NAD+ +
H2O
=
L-histidine
+ 2 NADH + 2 H+

Synonyms

11412251, BN980_GECA03s06082g, BsHDH, GcHDH, HDH, HIS4 protein, HisD, histidinol dehydrogenase, HLDase, L-histidinol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.23 histidinol dehydrogenase

KI Value

KI Value on EC 1.1.1.23 - histidinol dehydrogenase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0032
2-amino-3-(1H-imidazol-4-yl)-N'-[(E)-(4-phenoxyphenyl)methylidene]propanehydrazide
pH 7.2, 25°C
0.00047
2-amino-3-(1H-imidazol-4-yl)-N'-[(E)-(naphthalen-2-yl)methylidene]propanehydrazide
pH 7.2, 25°C
0.00064
2-amino-N'-[(E)-(4-chlorophenyl)methylidene]-3-(1H-imidazol-4-yl)propanehydrazide
pH 7.2, 25°C
0.013
2-amino-N'-[(E)-(4-fluorophenyl)methylidene]-3-(1H-imidazol-4-yl)propanehydrazide
pH 7.2, 25°C
additional information
additional information
inhibition kinetics of hydrozone derivative inhibitors with enzyme MtHisD
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