1.1.1.218: morphine 6-dehydrogenase

This is an abbreviated version!
For detailed information about morphine 6-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.218

Reaction

morphine
+
NAD(P)+
=
morphinone
+
NAD(P)H
+
H+

Synonyms

AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.218 morphine 6-dehydrogenase

IC50 Value

IC50 Value on EC 1.1.1.218 - morphine 6-dehydrogenase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0013 - 0.073
Hexestrol
0.0032 - 0.037
hinokitiol
0.05
icarisid II
Oryctolagus cuniculus
J7M9D0
above, pH 7.4, 25°C, recombinant enzyme
0.013
ikarisoside A
Oryctolagus cuniculus
J7M9D0
pH 7.4, 25°C, recombinant enzyme
0.02
kaempferol
Oryctolagus cuniculus
J7M9D0
above, pH 7.4, 25°C, recombinant enzyme
0.0064
noranhydroicaritin
Oryctolagus cuniculus
J7M9D0
pH 7.4, 25°C, recombinant enzyme
0.00065 - 0.007
Phenolphthalein
0.026
quercetin
Oryctolagus cuniculus
J7M9D0
pH 7.4, 25°C, recombinant enzyme
0.04
quercitrin
Oryctolagus cuniculus
J7M9D0
pH 7.4, 25°C, recombinant enzyme
0.05
zearalenone
Oryctolagus cuniculus
J7M9D0
above, pH 7.4, 25°C, recombinant enzyme