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1.1.1.218: morphine 6-dehydrogenase

This is an abbreviated version, for detailed information about morphine 6-dehydrogenase, go to the full flat file.

Reaction

morphine
+
NAD(P)+
=
morphinone
+
NAD(P)H
+
H+

Synonyms

AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.218 morphine 6-dehydrogenase

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Results
in table
1
Activating Compound
171
AA Sequence
2
CAS Registry Number
4
Cloned(Commentary)
10
Cofactor
9
Engineering
3
General Information
4
General Stability
13
IC50 Value
64
Inhibitors
43
KM Value [mM]
8
Localization
11
Molecular Weight [Da]
8
Natural Substrates/ Products (Substrates)
187
Organism
3
Pathway
14
pH Optimum
3
pH Stability
5
Purification (Commentary)
3
Reaction
4
Reaction Type
19
Reference by Title
20
Source Tissue
7
Specific Activity [micromol/min/mg]
5
Storage Stability
55
Substrates and Products (Substrate)
4
Subunits
7
Synonyms
1
Systematic Name
8
Temperature Optimum [°C]
3
Turnover Number [1/s]
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