1.1.1.206: tropinone reductase I
This is an abbreviated version!
For detailed information about tropinone reductase I, go to the full flat file.
Word Map on EC 1.1.1.206
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1.1.1.206
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tropane
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reductases
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hyoscyamine
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scopolamine
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datura
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pseudotropine
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stramonium
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solanaceae
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calystegines
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putrescine
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n-methyltransferase
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solanaceous
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3-quinuclidinone
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synthesis
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nortropane
- 1.1.1.206
-
tropane
- reductases
- hyoscyamine
- scopolamine
- datura
- pseudotropine
- stramonium
- solanaceae
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calystegines
- putrescine
- n-methyltransferase
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solanaceous
- 3-quinuclidinone
- synthesis
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nortropane
Reaction
Synonyms
BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, EC 1.1.1.293, More, TR-I, TR1, TRI, Tri2, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, tropinone reductase-I 2, WcTR-I, WsTR-I, WsTR-I protein
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.1.1.206 - tropinone reductase I
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REACTION DIAGRAM
tropinone + NADPH
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last step in biosynthesis of tropine
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r
tropine + NADP+
tropinone + NADPH
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role in the pathway for tropine catabolism
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-
r
tropine + NADP+
tropinone + NADPH
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role in the pathway for tropine catabolism
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-
r
pseudotropine + NADP+
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tropinone reductase II
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-
?
tropinone + NADPH + H+
pseudotropine + NADP+
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tropinone reductase II
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-
?
tropine + NADP+
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tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
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-
?
tropinone + NADPH + H+
tropine + NADP+
reaction of tropinone reductase I, EC 1.1.1.206, tropane alkaloid biosynthesis, overview
leading to formation of tropane alkaloids
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?
tropinone + NADPH + H+
tropine + NADP+
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tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
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-
r
tropinone + NADPH + H+
tropine + NADP+
tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
-
-
?
tropinone + NADPH + H+
tropine + NADP+
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tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
-
-
?
tropinone + NADPH + H+
tropine + NADP+
-
tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
-
-
?
tropinone + NADPH + H+
tropine + NADP+
-
tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
-
-
?
tropinone + NADPH + H+
tropine + NADP+
-
tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
-
-
r
tropinone + NADPH + H+
tropine + NADP+
direction of biosynthesis
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-
r
tropinone + NADPH + H+
tropine + NADP+
Scopolia atropoides
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tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine
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-
?
tropinone + NADPH + H+
tropine + NADP+
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the enzyme is involved in tropane alkaloid biosynthesis, e.g. of (S)-hyoscyamine, overview
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-
r
tropinone + NADPH + H+
tropine + NADP+
Solanum tuberosum tropinone reductase I reduces tropinone in vivo
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-
r
tropinone + NADPH + H+
tropine + NADP+
the reaction direction of tropinone reduction is predominantly operational in planta
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-
r
?
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the bifunctional enzyme of Cochlearia officinalis is not stereospecific, in contrast to the Solanaceae species, and catalyzes both tropinone reductase reactions, a tyrosine residue in the active site of Cochlearia officinalis TR is responsible for binding and orientation of tropinone, overview
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-
?
additional information
?
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the enzyme TR-I has a wide substrate specificity but does not cover the substrates of other well-known plant SDR related to menthol metabolism
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?
additional information
?
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the enzyme TR-I has a wide substrate specificity but does not cover the substrates of other well-known plant SDR related to menthol metabolism
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-
?