1.1.1.206: tropinone reductase I

This is an abbreviated version!
For detailed information about tropinone reductase I, go to the full flat file.

Word Map on EC 1.1.1.206

1.1.1.206

tropane

reductases

hyoscyamine

scopolamine

datura

pseudotropine

stramonium

solanaceae

calystegines

putrescine

n-methyltransferase

solanaceous

3-quinuclidinone

synthesis

nortropane

Reaction

Synonyms

BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, EC 1.1.1.293, More, TR-I, TR1, TRI, Tri2, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, tropinone reductase-I 2, WcTR-I, WsTR-I, WsTR-I protein

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.206 tropinone reductase I

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Results	in table
1	Activating Compound
113	AA Sequence
3	Application
1	CAS Registry Number
21	Cloned(Commentary)
37	Cofactor
1	Crystallization (Commentary)
4	Expression
29	General Information
22	Inhibitors
25	kcat/KM [mM/s]
62	KM Value [mM]
3	Metals/Ions
12	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
61	Organism
5	Pathway
22	pH Optimum
3	pH Range
1	pH Stability
4	pI Value
9	Protein Variants
14	Purification (Commentary)
1	Reaction
3	Reaction Type
59	Reference
51	Source Tissue
19	Specific Activity [micromol/min/mg]
5	Storage Stability
157	Substrates and Products (Substrate)
19	Subunits
67	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
12	Temperature Stability [°C]
24	Turnover Number [1/s]

KM Value

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KM Value on EC 1.1.1.206 - tropinone reductase I

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0.004 - 2.11

3-methylcyclohexanone

2 entries

0.167 - 5.17

3-quinuclidinone

3 entries

0.003

4-ethylcyclohexanone

Hyoscyamus niger

348024

0.001 - 8.71

4-methylcyclohexanone

3 entries

0.003

8-thiabicyclo(3,2,1)octane-3-one

Hyoscyamus niger

348024

0.231

N-Methyl-4-piperidone

Hyoscyamus niger

348024

1.74

N-methylpiperidine

Withania somnifera

U5PUZ1

recombinant enzyme, pH 6.7, 30°C

741278

NADH

Hyoscyamus niger

348024

0.013 - 0.208

NADP+

8 entries

0.00043 - 0.127

NADPH

7 entries

0.073 - 2

nortropine

2 entries

3.03

Nortropinone

Datura stramonium

347967

0.91

Scopine

Datura stramonium

347967

0.006 - 114.9

Tropine

9 entries

0.21 - 40.9

tropinone

15 entries

additional information

12 entries