1.1.1.201: 7beta-hydroxysteroid dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 7beta-hydroxysteroid dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

7beta-HSD, 7beta-HSDH, 7beta-hydroxysteroid dehydrogenase, More, NADP-dependent 7beta-hydroxysteroid dehydrogenase, RUMGNA_02585

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)

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Results	in table
15	AA Sequence
5	Application
1	CAS Registry Number
6	Cloned(Commentary)
22	Cofactor
2	Crystallization (Commentary)
4	General Information
2	General Stability
2	Inhibitors
12	kcat/KM [mM/s]
39	KM Value [mM]
5	Localization
7	Molecular Weight [Da]
50	Natural Substrates/ Products (Substrates)
28	Organism
3	Pathway
2	PDB ID
12	pH Optimum
1	pH Range
19	Protein Variants
7	Purification (Commentary)
2	Reaction
3	Reaction Type
26	Reference
12	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
88	Substrates and Products (Substrate)
9	Subunits
32	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
7	Temperature Stability [°C]
17	Turnover Number [1/s]

Sequence

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Sequence on EC 1.1.1.201 - 7beta-hydroxysteroid dehydrogenase (NADP+)

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UNIPROT

ENTRY NAME

ORGANISM

NO. OF AA

NO. OF TRANSM. HELICES

MOLECULAR WEIGHT[Da]

SOURCE

SEQUENCE

LOCALIZATION PREDICTIONThe reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).

G9FRD6 pBLAST

HSDHB_CLOSR

Clostridium sardiniense

261

0

29383

Swiss-Prot

Show Sequence

-

A4ECA9 pBLAST

HSDHB_COLAA

Collinsella aerofaciens (strain ATCC 25986 / DSM 3979 / JCM 10188 / KCTC 3647 / NCTC 11838 / VPI 1003)

263

0

28753

Swiss-Prot

Show Sequence

-

R9UAM1 pBLAST

HSDHB_RUMGN

Ruminococcus gnavus

263

0

29289

Swiss-Prot

Show Sequence

-

A7B4V1 pBLAST

HSDHB_RUMGV

Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9)

263

0

29289

Swiss-Prot

Show Sequence

-

Q8HZJ8 pBLAST

DHI1_BOVIN

Bos taurus

292

1

32309

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 2)

Q6QLL4 pBLAST

DHI1_CAVPO

Cavia porcellus

300

1

33226

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

P28845 pBLAST

DHI1_HUMAN

Homo sapiens

292

1

32401

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 2)

Q6R0J2 pBLAST

DHI1_MESAU

Mesocricetus auratus

292

1

32305

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

P50172 pBLAST

DHI1_MOUSE

Mus musculus

292

1

32364

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

Q7M3I4 pBLAST

DHI1_RABIT

Oryctolagus cuniculus

292

1

32125

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

P16232 pBLAST

DHI1_RAT

Rattus norvegicus

288

0

31883

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 2)

Q29608 pBLAST

DHI1_SAISC

Saimiri sciureus

291

1

32364

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 2)

P51975 pBLAST

DHI1_SHEEP

Ovis aries

292

1

32154

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 2)

D5A7S2 pBLAST

D5A7S2_DROME

Drosophila melanogaster

126

0

13392

TrEMBL

Show Sequence

other Location (Reliability: 2)

E3TDR7 pBLAST

E3TDR7_ICTPU

Ictalurus punctatus

260

0

27009

TrEMBL

Show Sequence

Mitochondrion (Reliability: 2)

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