1.1.1.187: GDP-4-dehydro-D-rhamnose reductase

This is an abbreviated version, for detailed information about GDP-4-dehydro-D-rhamnose reductase, go to the full flat file.

Reaction

GDP-alpha-D-rhamnose
+
NAD(P)+
=
GDP-4-dehydro-alpha-D-rhamnose
+
NAD(P)H
+
H+

Synonyms

GDP KR reductase, GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-D-rhamnose reductase, guanosine diphosphate-4-keto-D-rhamnose reductase, RMD, tld gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.187 GDP-4-dehydro-D-rhamnose reductase

General Information

General Information on EC 1.1.1.187 - GDP-4-dehydro-D-rhamnose reductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
effect of deficiency in GDP-D-rhamnose biosynthetic genes, including GDP-4-keto-6-deoxy-D-mannose reductase, on lipopolysaccharide structure and pathogenicity in soybean, Glycine max cv. Shirofumi. The mutant strain DELTArmd shows highly reduced antimicrobial susceptibility with chloramphenicol, ampicillinm or spectinomycin. The mutant DELTArmd strain also shows increased degrees of adhesion to the polystyrene surface of the micro-titrate plates. It has higher hydrophobicity of the cell surface than the wild-type strain, but has normal flagellin glycans