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1.1.1.179: D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)

This is an abbreviated version!
For detailed information about D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming), go to the full flat file.

Reaction

D-xylose
+
NADP+
=
D-xylono-1,5-lactone
+
NADPH
+
H+

Synonyms

D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, D-xylose 1-dehydrogenase (NADP), D-xylose dehydrogenase, D-xylose-NADP dehydrogenase, D-xylose:NADP+ oxidoreductase, NADP+-dependent D-xylose dehydrogenase, NADP+:D-xylose dehydrogenase, XDH, xyd1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)

Substrates Products

Substrates Products on EC 1.1.1.179 - D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
camphorquinone + NADPH
(1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+
show the reaction diagram
-
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,5-lactone + NADPH + H+
show the reaction diagram
-
-
-
-
r
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
show the reaction diagram
D-glucose + NAD(P)+
D-gluconolactone + NAD(P)H
show the reaction diagram
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
D-glucose + NADP+
D-gluconolactone + NADPH + H+
show the reaction diagram
reaction is catalyzed with 70fold lower catalytic efficiency (kcat/KM) compared to activity with D-xylose + NADP*
-
-
?
D-mannose + NADP+
D-mannono-1,5-lactone + NADPH
show the reaction diagram
D-ribose + NADP+
?
show the reaction diagram
D-ribose + NADP+
? + NADPH
show the reaction diagram
A8BT09
low activity
-
-
?
D-ribose + NADP+
D-ribonolactone + NADPH + H+
show the reaction diagram
reaction is catalyzed with 1.8fold lower catalytic efficiency (kcat/KM) compared to activity with D-xylose + NADP*
-
-
?
D-xylose + NAD(P)+
D-xylonolactone + NAD(P)H
show the reaction diagram
is highly specific for D-xylose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
show the reaction diagram
D-xylose + NAD+
D-xylonolactone + NADH + H+
show the reaction diagram
Vmax/Km for NADP+ is 7fold higher than Vmax/KM for NAD+
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
show the reaction diagram
D-xylose + NADP+
D-xylonolactone + NADPH + H+
show the reaction diagram
L-arabinose + NADP+
L-arabinono-1,4-lactone + NADPH
show the reaction diagram
L-arabinose + NADP+
L-arabinono-1,4-lactone + NADPH + H+
show the reaction diagram
-
44% of the activity with D-xylose
-
-
?
trans-benzene dihydrodiol + NADP+
?
show the reaction diagram
trans-naphthalene dihydrodiol + NADP+
?
show the reaction diagram
additional information
?
-