1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase

This is an abbreviated version!
For detailed information about hydroxycyclohexanecarboxylate dehydrogenase, go to the full flat file.

Reaction

Show molfile — (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate

Synonyms

(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase, dihydroxycyclohexanecarboxylate dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase

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All data fields related to EC 1.1.1.166
Results	in table
11	AA Sequence
1	CAS Registry Number
1	Cofactor
9	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
1	Organism
2	pH Optimum
2	pH Range
1	Purification (Commentary)
1	Reaction
3	Reaction Type
1	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
7	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name

Reaction

Reaction on EC 1.1.1.166 - hydroxycyclohexanecarboxylate dehydrogenase

for references in articles please use BRENDA:EC1.1.1.166

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(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+

Acts on hydroxycyclohexanecarboxylates that have an equatorial carboxyl group at C-1, an axial hydroxyl group at C-3 and an equatorial hydroxyl group or carbonyl group at C-4, including (-)-quinate and (-)-shikimate