1.1.1.144: perillyl-alcohol dehydrogenase

This is an abbreviated version!
For detailed information about perillyl-alcohol dehydrogenase, go to the full flat file.

Reaction

Synonyms

ADH, dehydrogenase, perillyl alcohol, perillyl alcohol dehydrogenase, SdPOHDH

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.144 perillyl-alcohol dehydrogenase

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Results	in table
1	Activating Compound
97	AA Sequence
1	Application
1	CAS Registry Number
1	Cloned(Commentary)
6	Cofactor
10	Inhibitors
3	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
7	Organism
3	Pathway
2	pH Optimum
2	pH Range
1	Protein Variants
2	Purification (Commentary)
1	Reaction
3	Reaction Type
7	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
16	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.1.1.144 - perillyl-alcohol dehydrogenase

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Ag+

Pseudomonas sp.

0.005 mM, complete inhibition, prevented by 10 mM glutathione

285942

Cu2+

Pseudomonas sp.

5 mM, complete inhibition, prevented by 5 mM glutathione

285942

Hg2+

Pseudomonas sp.

0.005 mM, complete inhibition, prevented by 10 mM glutathione

285942

iodoacetate

Pseudomonas sp.

10 mM, 95% inhibition, prevented by 10 mM glutathione

285942

NADH

Pseudomonas sp.

competitive inhibition

285942

Ni2+

Pseudomonas sp.

2 mM, 75% inhibition, complete reversion with 5 mM EDTA

285942

o-phenanthroline

Pseudomonas sp.

at concentrations higher than 3 mM and low concentration of NAD+, about 50% inhibition

285942

p-hydroxymercuribenzoate

Pseudomonas sp.

0.005 mM, complete inhibition, prevented by 10 mM glutathione

285942

Zn2+

Pseudomonas sp.

2 mM, 75% inhibition, complete reversion with 10 mM EDTA

285942

additional information

Pseudomonas sp.

glucose represses the induction of the enzyme by limonene

285942