1.1.1.122: D-threo-aldose 1-dehydrogenase
This is an abbreviated version!
For detailed information about D-threo-aldose 1-dehydrogenase, go to the full flat file.
Reaction
Synonyms
(2S,3R)-aldose dehydrogenase, FDH, L-fucose (D-arabinose) dehydrogenase, L-fucose dehydrogenase, Sso1300
ECTree
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Cofactor
Cofactor on EC 1.1.1.122 - D-threo-aldose 1-dehydrogenase
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NAD+
the enzyme is specific for sugars with D-arabinose-type hydroxyl group stereo-configurations at C3 and C4. This configuration is shared among the hexoses L-fucose (6-deoxy-L-galactose) and L-galactose, and the pentose D-ribose. Although the highest activity is observed with L-fucose in combination with NAD+, the remaining sugars are oxidized at higher rates using NADP+
-
30% of the activity compared to NAD+, L-fucose dehydrogenation