188.8.131.52: 3-dehydrosphinganine reductase
This is an abbreviated version!
For detailed information about 3-dehydrosphinganine reductase, go to the full flat file. Reaction
NADP + +
NADPH H+ Synonyms
3-KDS reductase, 3-ketodihydrosphingosine reductase, 3-ketosphinganine reductase, 3-oxosphinganine reductase, 3-oxosphinganine:NADPH oxidoreductase, 3KDSR, D-3-dehydrosphinganine reductase, D-3-oxosphinganine reductase, D-3-oxosphinganine:B-NADPH oxidoreductase, DSR, FVT-1, Fvt1, h-FTV-1, KDS reductase, Ksr1p, KsrA, m-FTV-1, More, TSC10, TSC10A, Tsc10p
General Information on EC 184.108.40.206 - 3-dehydrosphinganine reductase
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perturbation of sphingolipid biosynthesis in the Arabidopsis tsc10a mutant leads to an altered leaf ionome, including increases in Na, K, and Rb and decreases in Mg, Ca, Fe, and Mo, associated with increases in root suberin and alterations in Fe homeostasis. Loss of function of both TSC10A and TSC10B Is lethal in Arabidopsis thaliana
the enzyme is involved in de novo generation of ceramide and in invertebrate stress response
3-KDS reductase is essential for sphingolipid biosynthesis. Reduced 3-KDS reductase activity in Arabidopsis thaliana roots drives changes in the leaf Ionome