Sequence of CBADH_PSEUC
EC Number:3.8.1.7
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride
Other sequences found for EC No. 3.8.1.7
General information:
Sequence
0 MYEAIGHRVE DGVAEITIKL PRHRNALSVK AMQEVTDALN RAEEDDSVGA VMITGAEDAF
60 CAGFYLREIP LDKGVAGVRD HFRIGALWWH QMIHKIIRVK RPVLAAINGV AAGGGLGISL
120 ASDMAICADS AKFVCAWHTI GIGNDTATSY SLARIVGMRR AMELMLTNRT LYPEEAKDWG
180 LVSRVYPKDD FREVAWKVAR ELAAAPTHLQ VMAKERFHAG WMQPVEECTE FEIQNVIASV
240 THPHFMPCLT EFLDGHRADR PQVELPAGV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
141289
Babbitt P.C.,Kenyon G.L.,Martin B.M.,Charest H.,Slyvestre M.,Scholten J.D.,Chang K.H.,Liang P.H.,Dunaway-Mariano D.
Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases.
Biochemistry
31
5594-5604
1992
141291
Loffler F.,Lingens F.,Muller R.
Dehalogenation of 4-chlorobenzoate. Characterisation of 4-chlorobenzoyl-coenzyme A dehalogenase from Pseudomonas sp. CBS3.
Biodegradation
6
203-212
1995
141292
Chang K.H.,Liang P.H.,Beck W.,Scholten J.D.,Dunaway-Mariano D.
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.
Biochemistry
31
5605-5610
1992
141293
Liang P.H.,Yang G.,Dunaway-Mariano D.
Specificity of 4-chlorobenzoyl coenzyme A dehalogenase catalyzed dehalogenation of halogenated aromatics.
Biochemistry
32
12245-12250
1993
141294
Yang G.,Liu R.Q.,Taylor K.L.,Xiang H.,Price J.,Dunaway-Mariano D.
Identification of active site residues essential to 4-chlorobenzoyl-coenzyme A dehalogenase catalysis by chemical modification and site directed mutagenesis.
Biochemistry
35
10879-10885
1996
141295
Taylor K.L.,Xiang H.,Liu R.Q.,Yang G.,Dunaway-Mariano D.
Investigation of substrate activation by 4-chlorobenzoyl-coenzyme A dehalogenase.
Biochemistry
36
1349-1361
1997
141296
Luo L.,Taylor K.L.,Xiang H.,Wei Y.,Zhang W.,Dunaway-Mariano D.
Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis.
Biochemistry
40
15684-15692
2001
141297
Dong J.,Lu X.,Wei Y.,Luo L.,Dunaway-Mariano D.,Carey P.R.
The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation.
Biochemistry
42
9482-9490
2003
141298
Wu J.,Xu D.,Lu X.,Wang C.,Guo H.,Dunaway-Mariano D.
Contributions of long-range electrostatic interactions to 4-chlorobenzoyl-CoA dehalogenase catalysis: a combined theoretical and experimental study.
Biochemistry
45
102-112
2006
141299
Benning M.M.,Taylor K.L.,Liu R.-Q.,Yang G.,Xiang H.,Wesenberg G.,Dunaway-Mariano D.,Holden H.M.
Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 A resolution: an enzyme catalyst generated via adaptive mutation.
Biochemistry
35
8103-8109
1996
141300
Zhang W.,Wei Y.,Luo L.,Taylor K.L.,Yang G.,Dunaway-Mariano D.,Benning M.M.,Holden H.M.
Histidine 90 function in 4-chlorobenzoyl-coenzyme a dehalogenase catalysis.
Biochemistry
40
13474-13482
2001
