EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
glia |
primary culture of mixed glia. Incubation of cultures in the presence of fibrillar amyloid beta1-42 induces the assembly and the activation of NADPH oxidase, and triggers the production of superoxide anion-derived reactive oxygen species. Pretreatment of microglia with melatonin dose-dependently prevents the activation of NADPH oxidase and decreases the production of reactive oxygen species. Melatonin inhibits the phosphorylation of the p47phox subunit of NADPH oxidase via a PI3K/Akt-dependent signalling pathway, blocks the translocation of p47phox and p67phox subunit to the membrane, down-regulates the binding of p47phox to gp91phox, and impairs the assembly of NADPH oxidase |
688627 |
2.7.11.24 | mitogen-activated protein kinase |
glia |
mixed glial cultures |
702065 |
3.1.4.11 | phosphoinositide phospholipase C |
glia |
- |
715713 |
3.1.4.3 | phospholipase C |
glia |
primary |
-, 716352 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
glia |
olfactory bulb ensheathing glia in explant cultures |
653364 |
3.3.2.10 | soluble epoxide hydrolase |
glia |
restricted primarily to oligodendrocytes in the white matter |
708573 |
4.2.1.1 | carbonic anhydrase |
glia |
- |
33547 |
5.1.1.18 | serine racemase |
glia |
- |
706532 |
5.3.4.1 | protein disulfide-isomerase |
glia |
- |
3079 |
6.3.2.41 | N-acetylaspartylglutamate synthase |
glia |
cerebellar glia cell |
728179 |