EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.4.16.2 | lysosomal Pro-Xaa carboxypeptidase |
aorta |
aortic aneurysm and normal aorta |
36275 |
3.4.23.5 | cathepsin D |
aorta |
- |
36921 |
4.4.1.5 | lactoylglutathione lyase |
aorta |
- |
37413, 729179 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
- |
3200, 37458, 37460, 37461, 37462, 37463, 37465, 37466, 37467, 37468, 37469, 37470, 37475, 37476, 37477, 37478, 37479, 37480, 37485, 660924, 681029 |
3.1.1.13 | sterol esterase |
aorta |
- |
133849 |
3.1.3.16 | protein-serine/threonine phosphatase |
aorta |
smooth muscle |
134605 |
3.4.13.18 | cytosol nonspecific dipeptidase |
aorta |
normal and from patients with aortic aneurysms |
137197 |
3.6.1.13 | ADP-ribose diphosphatase |
aorta |
- |
209946 |
3.6.1.5 | apyrase |
aorta |
- |
210132, 210162 |
3.6.1.5 | apyrase |
aorta |
aortic endothelial cells |
210150 |
3.6.1.5 | apyrase |
aorta |
smooth muscle cells |
210167 |
3.6.1.5 | apyrase |
aorta |
intima and media layers |
210168 |
7.6.2.1 | P-type phospholipid transporter |
aorta |
epithelial cells |
246839 |
7.2.2.13 | Na+/K+-exchanging ATPase |
aorta |
- |
246966, 735119 |
1.1.1.179 | D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) |
aorta |
- |
286124 |
1.6.2.4 | NADPH-hemoprotein reductase |
aorta |
- |
-, 288616 |
1.4.3.13 | protein-lysine 6-oxidase |
aorta |
- |
391736, 391737, 391739, 391742, 655021, 659558, 675286, 684802, 695968, 699875, 713462, 724520 |
1.8.4.2 | protein-disulfide reductase (glutathione) |
aorta |
- |
394828 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
aorta |
embryo |
439200 |
2.1.1.71 | phosphatidyl-N-methylethanolamine N-methyltransferase |
aorta |
- |
485560 |
2.3.1.26 | sterol O-acyltransferase |
aorta |
41fold induction of activity after 60 days of cholesterol feeding |
486683 |
2.3.1.26 | sterol O-acyltransferase |
aorta |
atheroschlerotic tissue |
486688, 486703 |
2.3.1.26 | sterol O-acyltransferase |
aorta |
- |
486688, 486698, 486703 |
2.3.1.26 | sterol O-acyltransferase |
aorta |
extremely low activity |
486704 |
2.4.1.87 | N-acetyllactosaminide 3-alpha-galactosyltransferase |
aorta |
- |
489479 |
2.7.11.16 | G-protein-coupled receptor kinase |
aorta |
- |
491168 |
2.5.1.57 | N-acylneuraminate-9-phosphate synthase |
aorta |
- |
637818 |
2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase |
aorta |
intimal layer |
638569 |
2.6.1.42 | branched-chain-amino-acid transaminase |
aorta |
endothelial cells |
640023 |
2.7.11.18 | myosin-light-chain kinase |
aorta |
thoracic |
640625 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
aorta |
smooth muscle |
640688 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
aorta |
smooth muscle |
640742, 640743 |
2.7.3.2 | creatine kinase |
aorta |
- |
642371 |
2.7.7.23 | UDP-N-acetylglucosamine diphosphorylase |
aorta |
- |
643065 |
2.7.7.30 | fucose-1-phosphate guanylyltransferase |
aorta |
- |
645224 |
2.7.8.15 | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase |
aorta |
- |
645351, 645353 |
2.8.2.15 | steroid sulfotransferase |
aorta |
aortic smooth muscle cell line CRL-1999 |
645740 |
2.8.2.4 | estrone sulfotransferase |
aorta |
female aortic smooth muscle cell line CRL-1999 cell |
645740 |
3.1.6.2 | steryl-sulfatase |
aorta |
abdominal, STS expression levels are higher in the vascular smooth muscle cells obtained from female aortas with mild atherosclerotic changes than in those with severe atherosclerotic changes in male aortas regardless of atherosclerotic changes |
645740 |
3.1.6.2 | steryl-sulfatase |
aorta |
adult |
645797 |
3.1.2.2 | palmitoyl-CoA hydrolase |
aorta |
- |
646158 |
3.1.2.20 | acyl-CoA hydrolase |
aorta |
- |
646158 |
3.1.3.53 | [myosin-light-chain] phosphatase |
aorta |
fragments of the 110 kDa subunit |
646358 |
3.1.3.53 | [myosin-light-chain] phosphatase |
aorta |
fetal, same MLCP activities in normal and pulmonary hypertensive fetal sheep |
646359 |
3.1.3.53 | [myosin-light-chain] phosphatase |
aorta |
embryonic and adult, smooth muscle, throughout development, exclusive expression of the splice-in myosin-targeting subunit isoform |
646360 |
3.3.2.7 | hepoxilin-epoxide hydrolase |
aorta |
- |
647027 |
3.1.4.11 | phosphoinositide phospholipase C |
aorta |
PLC delta3 and delta4 |
649088 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
aorta |
highly expressed in vascular endothelium |
650399 |
3.4.14.2 | dipeptidyl-peptidase II |
aorta |
- |
651779 |
1.11.1.6 | catalase |
aorta |
- |
655134 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
aorta |
1.2% of the activity in liver |
655483 |
4.1.1.19 | arginine decarboxylase |
aorta |
highest activity of all tissues tested |
656583 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
aorta |
level of GM3 synthase in membrane-fractions isolated from the atherosclerotic intima are higher compared to those in non-dieased arterial tissue |
657703 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
aorta |
atherosclerotic aortic intima |
658140 |
1.4.3.13 | protein-lysine 6-oxidase |
aorta |
LOX, LOXL, LOXL3, low expression level of LOXL2 |
658189 |
1.14.12.17 | nitric oxide dioxygenase |
aorta |
endothelial cells |
658747 |
1.4.3.13 | protein-lysine 6-oxidase |
aorta |
co-localization of LOX and LOXL |
659751 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
aorta |
expression only of LH2long |
659845 |
1.13.11.34 | arachidonate 5-lipoxygenase |
aorta |
expression is not significantly different between diabetic and control rats. Activation of the 5-lipoxygenase previously reported in streptozotocin-induced diabetic rats can be explained by an augmented sensitivity to cysteinyl leukotrienes in the diabetic aorta |
660412 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
high expression of isozymes PKG-1alpha and PKG-1beta |
660671 |
2.7.10.1 | receptor protein-tyrosine kinase |
aorta |
smooth muscle |
660727 |
2.7.1.52 | fucokinase |
aorta |
- |
641674, 661521, 703298 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
smooth muscle |
661575 |
2.7.11.18 | myosin-light-chain kinase |
aorta |
- |
491268, 661664, 687732 |
2.7.11.13 | protein kinase C |
aorta |
- |
662054 |
6.3.4.5 | argininosuccinate synthase |
aorta |
endothelial cell |
662377 |
3.1.3.53 | [myosin-light-chain] phosphatase |
aorta |
and large capacitance vessels, predominantly expression of 3-exon-out/leucine-zipper positive MYPT 1 isoform |
663585 |
3.4.11.2 | membrane alanyl aminopeptidase |
aorta |
endothelial cell |
664320, 664501 |
3.4.22.B29 | calpain 9 |
aorta |
- |
664555 |
3.1.3.53 | [myosin-light-chain] phosphatase |
aorta |
expression of leucine-zipper positive isoform of MYPT 1 predominantes in healthy animal |
664610 |
4.1.1.22 | histidine decarboxylase |
aorta |
- |
665184 |
3.1.1.34 | lipoprotein lipase |
aorta |
aortic endothelial cells |
665649 |
3.1.3.4 | phosphatidate phosphatase |
aorta |
- |
665805 |
3.4.22.27 | cathepsin S |
aorta |
smooth muscle cells |
667140 |
3.4.24.15 | thimet oligopeptidase |
aorta |
aortic endothelial cell culture. Enzyme is sensitive to Gialpha2/3 inhibition. Under cyclic strain conditions, level of secreted enzyme increases 2.6fold |
667354 |
3.4.24.86 | ADAM 17 endopeptidase |
aorta |
atherosclerotic lesions of apolipoprotein E-deficient mice |
667364 |
3.4.24.34 | neutrophil collagenase |
aorta |
MMP-8 is localized to mesenchymal cells within the adventitia of the aortic wall |
668115 |
3.5.3.18 | dimethylargininase |
aorta |
- |
288970, 668120, 695485, 698209 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
aorta |
abdominal, expression level determination, especially in female aorta with mild atherosclerotic changes |
668413 |
7.2.2.9 | P-type Cu2+ transporter |
aorta |
- |
668543 |
2.7.8.27 | sphingomyelin synthase |
aorta |
- |
668729 |
2.7.8.27 | sphingomyelin synthase |
aorta |
high expression of SMS1 mRNA |
668729 |
1.1.1.21 | aldose reductase |
aorta |
vascular smooth muscle cells |
669468 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE1 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE10 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE11 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE2 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE3 |
670145 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE5 |
670145 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE6 |
670145 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE9 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE4 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE7 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE8 |
670145 |
3.5.3.1 | arginase |
aorta |
intact aorta |
670422 |
3.4.24.11 | neprilysin |
aorta |
tissue NEP activity and its protein and mRNA expression are lower in the late phase of the septic shock compared to the early phase of the shock and the control |
670860 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
aorta |
- |
491257, 491258, 640685, 671227 |
2.7.10.2 | non-specific protein-tyrosine kinase |
aorta |
endothelial cells, PYK2 |
673110 |
5.6.1.6 | channel-conductance-controlling ATPase |
aorta |
- |
675622 |
3.4.21.B26 | proprotein convertase 5 |
aorta |
PC5A dominates |
675967 |