EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
aorta |
atherogenic aorta |
693520 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
aorta |
26% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
aorta |
- |
701239 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
aorta |
- |
701239 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
aorta |
- |
741244 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
- |
685021, 750336 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE4 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE7 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
PDE8 |
670145 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
aorta |
weak activity |
685021 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
- |
711920, 711923 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE5 |
670145 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE6 |
670145 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
aorta |
PDE9 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
- |
679248 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE1 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE10 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE11 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE2 |
670145 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
aorta |
PDE3 |
670145 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
aorta |
3MST and cytosolic and mitochondrial cysteine aminotransferases are localized to endothelial cells of the thoracic aorta |
704359 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
aorta |
abdominal, expression level determination, especially in female aorta with mild atherosclerotic changes |
668413 |
1.5.1.34 | 6,7-dihydropteridine reductase |
aorta |
- |
741864 |
3.1.2.20 | acyl-CoA hydrolase |
aorta |
- |
646158 |
3.4.24.86 | ADAM 17 endopeptidase |
aorta |
- |
753291 |
3.4.24.86 | ADAM 17 endopeptidase |
aorta |
atherosclerotic lesions of apolipoprotein E-deficient mice |
667364 |
3.4.24.86 | ADAM 17 endopeptidase |
aorta |
intraluminal thrombus of human abdominal aortic aneurysm |
755575 |
3.4.24.86 | ADAM 17 endopeptidase |
aorta |
metalloproteases ADAM-9, ADAM-15, and ADAM-17 are upregulated in advanced human atherosclerotic lesions in samples from carotid, abdominal aortic, and femoral territories compared to samples from internal thoracic artery free of atherosclerotic plaques. ADAM-9, ADAM-15, and ADAM-17-expressing cells colocalize with CD68-positive cells of monocytic origin in the atherosclerotic plaques |
710868 |
3.4.24.81 | ADAM10 endopeptidase |
aorta |
- |
755575 |
3.4.24.B9 | ADAM9 endopeptidase |
aorta |
- |
710868 |
3.4.24.82 | ADAMTS-4 endopeptidase |
aorta |
- |
755457 |
3.4.24.82 | ADAMTS-4 endopeptidase |
aorta |
low expression in non-atherosclerotic aorta |
677894 |
3.4.24.B11 | ADAMTS1 endopeptidase |
aorta |
- |
755146 |
3.4.24.B12 | ADAMTS5 endopeptidase |
aorta |
- |
734180 |
4.6.1.1 | adenylate cyclase |
aorta |
- |
690360 |
3.6.1.13 | ADP-ribose diphosphatase |
aorta |
- |
209946 |
1.1.1.1 | alcohol dehydrogenase |
aorta |
the activity of the class I ADH isoenzyme is significantly lower in the wall of aortic aneurysm than in healthy aorta |
697802 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
aorta |
- |
711625 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
aorta |
- |
688446 |
1.2.3.1 | aldehyde oxidase |
aorta |
- |
693075 |
1.1.1.21 | aldose reductase |
aorta |
- |
286239, 668380, 711762, 711859 |
1.1.1.21 | aldose reductase |
aorta |
vascular smooth muscle cells |
669468 |
3.1.3.1 | alkaline phosphatase |
aorta |
- |
693930 |
3.4.17.23 | angiotensin-converting enzyme 2 |
aorta |
- |
762703 |
3.6.1.5 | apyrase |
aorta |
- |
210132, 210162 |
3.6.1.5 | apyrase |
aorta |
aortic endothelial cells |
210150 |
3.6.1.5 | apyrase |
aorta |
intima and media layers |
210168 |
3.6.1.5 | apyrase |
aorta |
smooth muscle cells |
210167 |
1.13.11.33 | arachidonate 15-lipoxygenase |
aorta |
- |
-, 684349, 742845 |
1.13.11.34 | arachidonate 5-lipoxygenase |
aorta |
expression is not significantly different between diabetic and control rats. Activation of the 5-lipoxygenase previously reported in streptozotocin-induced diabetic rats can be explained by an augmented sensitivity to cysteinyl leukotrienes in the diabetic aorta |
660412 |
3.5.3.1 | arginase |
aorta |
- |
688758 |
3.5.3.1 | arginase |
aorta |
intact aorta |
670422 |
4.1.1.19 | arginine decarboxylase |
aorta |
highest activity of all tissues tested |
656583 |
6.3.4.5 | argininosuccinate synthase |
aorta |
- |
690727, 690765 |
6.3.4.5 | argininosuccinate synthase |
aorta |
endothelial cell |
662377 |
2.6.1.42 | branched-chain-amino-acid transaminase |
aorta |
endothelial cells |
640023 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
aorta |
- |
491257, 491258, 640685, 671227 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
aorta |
smooth muscle |
640688 |
3.4.22.B29 | calpain 9 |
aorta |
- |
664555 |
3.4.22.52 | calpain-1 |
aorta |
- |
708018 |
3.4.22.53 | calpain-2 |
aorta |
- |
708151 |
3.4.22.53 | calpain-2 |
aorta |
relatively high m-calpain expression levels in the inferior arch |
708018 |
1.11.1.6 | catalase |
aorta |
- |
655134 |
2.1.1.6 | catechol O-methyltransferase |
aorta |
- |
686194 |
3.4.23.5 | cathepsin D |
aorta |
- |
36921 |
3.4.22.38 | cathepsin K |
aorta |
in the macrophage-rich regions of atherosclerotic plaques |
708148 |
3.4.22.15 | cathepsin L |
aorta |
increased level of cathepsin L in atherosclerotic lesions compared with healthy aortas |
695435 |
3.4.22.27 | cathepsin S |
aorta |
smooth muscle cells |
667140 |
3.4.22.43 | cathepsin V |
aorta |
expression in aorta valve, control valves and stenotic valves analyzed |
683107 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
- |
662462, 674575, 704619, 721982, 722222 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
aortic homogenate, neointima |
721982 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
high expression of isozymes PKG-1alpha and PKG-1beta |
660671 |
2.7.11.12 | cGMP-dependent protein kinase |
aorta |
smooth muscle |
661575 |
5.6.1.6 | channel-conductance-controlling ATPase |
aorta |
- |
675622 |
3.4.21.39 | chymase |
aorta |
- |
699756 |
2.7.3.2 | creatine kinase |
aorta |
- |
642371 |
4.4.1.1 | cystathionine gamma-lyase |
aorta |
- |
690352, 692207, 695134, 707582, 746708 |
3.4.13.18 | cytosol nonspecific dipeptidase |
aorta |
normal and from patients with aortic aneurysms |
137197 |
1.1.1.179 | D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) |
aorta |
- |
286124 |
3.5.3.18 | dimethylargininase |
aorta |
- |
288970, 668120, 695485, 698209 |
3.4.14.2 | dipeptidyl-peptidase II |
aorta |
- |
651779 |
3.4.24.71 | endothelin-converting enzyme 1 |
aorta |
- |
683318 |
3.4.24.71 | endothelin-converting enzyme 1 |
aorta |
determination of enzyme expression by immunohistochemical analysis on atherosclerotic and nonatherosclerotic vascular tissue using a combination of ECE-1 isoform-specific antibodies, distinct expression patterns for ECE-1a and ECE-1c, overview |
683440 |
3.4.24.71 | endothelin-converting enzyme 1 |
aorta |
increased ECE-1 protein content (immunohistochemistry, immunoblot) and mRNA expression (Northern blot) in apolipoprotein E-deficient mouse |
-, 699415 |
2.8.2.4 | estrone sulfotransferase |
aorta |
female aortic smooth muscle cell line CRL-1999 cell |
645740 |
1.8.5.8 | eukaryotic sulfide quinone oxidoreductase |
aorta |
- |
764408 |
3.2.1.18 | exo-alpha-sialidase |
aorta |
aortic smooth muscle |
695452 |
1.2.1.94 | farnesal dehydrogenase |
aorta |
- |
717961 |
2.7.1.52 | fucokinase |
aorta |
- |
641674, 661521, 703298 |
2.7.7.30 | fucose-1-phosphate guanylyltransferase |
aorta |
- |
645224 |
2.7.11.16 | G-protein-coupled receptor kinase |
aorta |
- |
491168 |
2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase |
aorta |
intimal layer |
638569 |
3.4.24.24 | gelatinase A |
aorta |
- |
754999 |
3.4.24.35 | gelatinase B |
aorta |
- |
697149, 699878 |
3.5.4.16 | GTP cyclohydrolase I |
aorta |
- |
698049, 698205, 698211 |
4.6.1.2 | guanylate cyclase |
aorta |
- |
691542, 691656, 693256, 693826 |
4.6.1.2 | guanylate cyclase |
aorta |
aortic ring |
693812 |
4.6.1.2 | guanylate cyclase |
aorta |
human aortic smooth muscle cells |
693087 |
4.6.1.2 | guanylate cyclase |
aorta |
primary aortic smooth muscle cells |
691841 |
4.6.1.2 | guanylate cyclase |
aorta |
vascular wall and smooth muscle cells |
691659 |