EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
adrenal cortex |
both 15-hydroxyprostaglandin dehydrogenase mRNA and protein levels are significantly higher in kidney cortex than in papilla. Enzyme is mainly localized to the tubular epithelial cells in kidney cortex and outer medulla |
684372 |
1.1.1.197 | 15-hydroxyprostaglandin dehydrogenase (NADP+) |
adrenal cortex |
- |
347830 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal cortex |
- |
706819, 728827 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal cortex |
zona fasciculata, zona reticularis |
665842 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal cortex |
- |
656654 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal cortex |
- |
-, 668428 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
- |
686518 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
of newborn mice |
686518 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
tumor tissues from patients with isolated micronodular adrenocortical disease and no mutations in the coding PDE8B sequence or any other related genes (PRKAR1A, PDE11A) show downregulated PDE8B expression compared to normal adrenal cortex. PDE8B is a PDE gene linked to isolated micronodular adrenocortical disease. It is a candidate causative gene for other adrenocortical lesions linked to the cAMP signaling pathway and possibly for tumors in other tissues |
686518 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adrenal cortex |
PDE2 |
668987 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal cortex |
- |
668413 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal cortex |
isozyme type 2 |
656091 |
3.1.3.2 | acid phosphatase |
adrenal cortex |
sinusoidal cells |
666100 |
3.13.2.1 | adenosylhomocysteinase |
adrenal cortex |
- |
137130 |
1.18.1.6 | adrenodoxin-NADP+ reductase |
adrenal cortex |
- |
718572, 718822, 719028, 719386, 719389, 719398, 719475, 719482, 719751, 719752, 719768, 719769 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
adrenal cortex |
- |
745756 |
2.8.2.14 | bile-salt sulfotransferase |
adrenal cortex |
- |
676007 |
2.7.11.11 | cAMP-dependent protein kinase |
adrenal cortex |
- |
662180 |
3.4.23.5 | cathepsin D |
adrenal cortex |
- |
36935 |
3.5.1.23 | ceramidase |
adrenal cortex |
- |
720471 |
2.7.11.12 | cGMP-dependent protein kinase |
adrenal cortex |
- |
760323 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
adrenal cortex |
- |
285412, 285413, 285414, 285415, 285416, 285417, 285418, 285419, 285420, 285421, 285424, 285425, 285426, 285427, 285428, 285429, 285430, 285431, 285432, 285433, 658811, 703418, 703625, 703876, 704039 |
1.14.15.5 | corticosterone 18-monooxygenase |
adrenal cortex |
- |
438757 |
3.4.24.71 | endothelin-converting enzyme 1 |
adrenal cortex |
- |
31470 |
2.8.2.4 | estrone sulfotransferase |
adrenal cortex |
- |
760317 |
4.3.2.9 | gamma-glutamylcyclotransferase |
adrenal cortex |
moderate expression |
720332 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
adrenal cortex |
- |
286980 |
3.4.11.7 | glutamyl aminopeptidase |
adrenal cortex |
- |
36025 |
4.6.1.2 | guanylate cyclase |
adrenal cortex |
- |
34865 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
adrenal cortex |
constitutive expression of HO-2 |
688006 |
4.3.1.3 | histidine ammonia-lyase |
adrenal cortex |
- |
34308 |
1.1.1.38 | malate dehydrogenase (oxaloacetate-decarboxylating) |
adrenal cortex |
- |
286698 |
1.5.1.15 | methylenetetrahydrofolate dehydrogenase (NAD+) |
adrenal cortex |
- |
-, 392084, 392085 |
3.4.24.64 | mitochondrial processing peptidase |
adrenal cortex |
- |
31387 |
1.4.3.4 | monoamine oxidase |
adrenal cortex |
of adrenal gland |
655721 |
4.2.1.11 | phosphopyruvate hydratase |
adrenal cortex |
- |
665841 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
adrenal cortex |
Northern blot analysis of human tissues |
659136 |
3.4.21.B26 | proprotein convertase 5 |
adrenal cortex |
- |
673910, 718009 |
3.4.21.B26 | proprotein convertase 5 |
adrenal cortex |
richest source of PC5A |
675967 |
3.1.3.16 | protein-serine/threonine phosphatase |
adrenal cortex |
- |
134673 |
3.4.23.B24 | signal peptide peptidase |
adrenal cortex |
- |
752819 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal cortex |
- |
285387, 285389, 285390, 285391, 285393, 285394, 285395, 285396, 285398, 285399, 285400, 285401, 285402, 285403, 285404, 285405, 285410, 285411, 673345, 724701 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal cortex |
capsular portion in zona glomerulosa cells, decapsular in zonae fasciculata and reticularis |
285392, 285397 |
1.14.14.19 | steroid 17alpha-monooxygenase |
adrenal cortex |
- |
692540, 726923, 727701, 727953 |
1.14.14.16 | steroid 21-monooxygenase |
adrenal cortex |
- |
285446, 673924, 734302, 735122 |
5.3.3.1 | steroid DELTA-isomerase |
adrenal cortex |
- |
721693 |
2.8.2.15 | steroid sulfotransferase |
adrenal cortex |
- |
645723, 645739 |
3.1.1.13 | sterol esterase |
adrenal cortex |
- |
133854 |