EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
Huh-7 cell |
- |
726080, 740536 |
1.1.1.170 | 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) |
Huh-7 cell |
- |
741051 |
1.1.1.26 | glyoxylate reductase |
Huh-7 cell |
GRHPR is reduced in proliferative Huh7 cells |
739241 |
1.1.1.29 | glycerate dehydrogenase |
Huh-7 cell |
- |
739241 |
1.1.1.79 | glyoxylate reductase (NADP+) |
Huh-7 cell |
GRHPR is reduced in proliferative Huh7 cells |
739241 |
1.13.11.53 | acireductone dioxygenase (Ni2+-requiring) |
Huh-7 cell |
- |
764433 |
1.14.11.16 | peptide-aspartate beta-dioxygenase |
Huh-7 cell |
- |
743130 |
1.14.14.154 | sterol 14alpha-demethylase |
Huh-7 cell |
- |
744274 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
Huh-7 cell |
- |
685997 |
1.14.14.23 | cholesterol 7alpha-monooxygenase |
Huh-7 cell |
- |
712675 |
1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
Huh-7 cell |
- |
701238 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
Huh-7 cell |
- |
745482 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
Huh-7 cell |
harboring the pFKI389neo/NS3-39/5.1 subgenomic replicon (Huh7 SGR, genotype 1b) |
746433 |
1.14.99.29 | deoxyhypusine monooxygenase |
Huh-7 cell |
- |
746299 |
1.14.99.38 | cholesterol 25-monooxygenase |
Huh-7 cell |
- |
745657 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
Huh-7 cell |
- |
694110 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
Huh-7 cell |
- |
700236 |
1.3.1.70 | DELTA14-sterol reductase |
Huh-7 cell |
- |
765069 |
1.3.1.72 | DELTA24-sterol reductase |
Huh-7 cell |
- |
712405, 746181 |
2.1.1.20 | glycine N-methyltransferase |
Huh-7 cell |
- |
658385 |
2.1.1.319 | type I protein arginine methyltransferase |
Huh-7 cell |
- |
756861 |
2.1.1.348 | mRNA m6A methyltransferase |
Huh-7 cell |
- |
756024, 756898 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
Huh-7 cell |
- |
733991 |
2.1.1.67 | thiopurine S-methyltransferase |
Huh-7 cell |
- |
688126 |
2.1.2.2 | phosphoribosylglycinamide formyltransferase 1 |
Huh-7 cell |
- |
736225 |
2.1.3.3 | ornithine carbamoyltransferase |
Huh-7 cell |
- |
757879 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
Huh-7 cell |
- |
756687, 757194 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
Huh-7 cell |
low expression of isoform LCAT1 |
719936 |
2.3.1.26 | sterol O-acyltransferase |
Huh-7 cell |
- |
684882 |
2.3.1.42 | glycerone-phosphate O-acyltransferase |
Huh-7 cell |
- |
756338 |
2.3.1.48 | histone acetyltransferase |
Huh-7 cell |
- |
736791, 757011 |
2.3.1.57 | diamine N-acetyltransferase |
Huh-7 cell |
- |
756390 |
2.3.1.85 | fatty-acid synthase system |
Huh-7 cell |
- |
703080 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
Huh-7 cell |
- |
737977, 757883 |
2.3.2.32 | cullin-RING-type E3 NEDD8 transferase |
Huh-7 cell |
- |
745773 |
2.4.1.133 | xylosylprotein 4-beta-galactosyltransferase |
Huh-7 cell |
- |
704930 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
Huh-7 cell |
- |
690613, 759648 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
Huh-7 cell |
the cells show lower enzyme activity |
736192 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
Huh-7 cell |
- |
735872, 758918 |
2.4.2.30 | NAD+ ADP-ribosyltransferase |
Huh-7 cell |
- |
736899 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
Huh-7 cell |
- |
764855 |
2.4.3.6 | N-acetyllactosaminide alpha-2,3-sialyltransferase |
Huh-7 cell |
- |
759169 |
2.6.1.44 | alanine-glyoxylate transaminase |
Huh-7 cell |
- |
759686 |
2.6.1.51 | serine-pyruvate transaminase |
Huh-7 cell |
- |
759686 |
2.7.1.12 | gluconokinase |
Huh-7 cell |
- |
762082 |
2.7.1.3 | ketohexokinase |
Huh-7 cell |
hepatocellular carcinoma cell |
739133 |
2.7.1.40 | pyruvate kinase |
Huh-7 cell |
- |
739755 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
Huh-7 cell |
- |
760861 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
Huh-7 cell |
- |
740845 |
2.7.12.1 | dual-specificity kinase |
Huh-7 cell |
- |
741425 |
2.7.7.84 | 2'-5' oligoadenylate synthase |
Huh-7 cell |
- |
762508 |
2.7.7.84 | 2'-5' oligoadenylate synthase |
Huh-7 cell |
OAS1 and OAS3 transcripts are constitutively expressed |
738223 |
2.7.8.27 | sphingomyelin synthase |
Huh-7 cell |
a hepatoma cell line |
691046 |
2.8.2.15 | steroid sulfotransferase |
Huh-7 cell |
- |
726332 |
2.8.2.2 | alcohol sulfotransferase |
Huh-7 cell |
- |
726332 |
2.8.2.2 | alcohol sulfotransferase |
Huh-7 cell |
hepatocellular carcinoma cell line |
645741 |
2.8.2.30 | [heparan sulfate]-glucosamine 3-sulfotransferase 3 |
Huh-7 cell |
- |
726527 |
2.8.2.4 | estrone sulfotransferase |
Huh-7 cell |
- |
760317 |
3.1.1.1 | carboxylesterase |
Huh-7 cell |
- |
715525 |
3.1.1.34 | lipoprotein lipase |
Huh-7 cell |
- |
749916 |
3.1.3.4 | phosphatidate phosphatase |
Huh-7 cell |
- |
709037, 752001 |
3.1.3.48 | protein-tyrosine-phosphatase |
Huh-7 cell |
- |
750305 |
3.1.3.5 | 5'-nucleotidase |
Huh-7 cell |
- |
752251 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
Huh-7 cell |
- |
730760 |
3.3.2.9 | microsomal epoxide hydrolase |
Huh-7 cell |
- |
731547, 732940 |
3.3.2.9 | microsomal epoxide hydrolase |
Huh-7 cell |
hepatoma cell line |
662917 |
3.4.11.1 | leucyl aminopeptidase |
Huh-7 cell |
IFN-alpha, IFN-beta, or IFN-gamma induce the expression of LAP at the mRNA and protein level. Transfection with the synthetic dsRNA poly(I-C) results in an increase in LAP mRNA levels. Transfection of Huh-7 cells with HCV RNA increases mRNA levels of LAP |
681245 |
3.4.11.2 | membrane alanyl aminopeptidase |
Huh-7 cell |
- |
707799 |
3.4.15.1 | peptidyl-dipeptidase A |
Huh-7 cell |
endogenously expressing ACE2 |
679876 |
3.4.16.6 | carboxypeptidase D |
Huh-7 cell |
- |
731593 |
3.4.17.22 | metallocarboxypeptidase D |
Huh-7 cell |
- |
731593 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
Huh-7 cell |
UCHL1 expression is low, which is well correlated with its promoter methylation status |
698156 |
3.4.21.112 | site-1 protease |
Huh-7 cell |
- |
687607 |
3.4.21.122 | transmembrane protease serine 2 |
Huh-7 cell |
- |
754535 |
3.4.21.122 | transmembrane protease serine 2 |
Huh-7 cell |
high expression level |
753655 |
3.4.21.73 | u-Plasminogen activator |
Huh-7 cell |
- |
731238, 731239 |
3.4.21.75 | Furin |
Huh-7 cell |
- |
732972 |
3.4.21.75 | Furin |
Huh-7 cell |
infected by heaptitis C virus |
718447 |
3.4.21.B26 | proprotein convertase 5 |
Huh-7 cell |
- |
675967 |
3.4.21.B41 | kallikrein 10 |
Huh-7 cell |
- |
708585 |
3.4.22.15 | cathepsin L |
Huh-7 cell |
- |
696565, 711056 |
3.4.22.52 | calpain-1 |
Huh-7 cell |
- |
708643 |
3.4.22.59 | caspase-6 |
Huh-7 cell |
- |
697089 |
3.4.22.59 | caspase-6 |
Huh-7 cell |
a human hepatoma cell line expressing the sodium taurocholate cotransporting polypeptide, Ntcp |
698943 |
3.4.22.61 | caspase-8 |
Huh-7 cell |
- |
717576 |
3.4.22.61 | caspase-8 |
Huh-7 cell |
caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines |
680244 |
3.4.22.61 | caspase-8 |
Huh-7 cell |
Huh7 hepatoma cell |
665899 |
3.4.24.18 | meprin A |
Huh-7 cell |
- |
754965 |
3.4.24.71 | endothelin-converting enzyme 1 |
Huh-7 cell |
- |
735130 |
3.4.24.86 | ADAM 17 endopeptidase |
Huh-7 cell |
- |
734505 |
3.4.24.B4 | matrix metalloproteinase-13 |
Huh-7 cell |
- |
713548 |
3.5.4.36 | mRNA(cytosine6666) deaminase |
Huh-7 cell |
- |
735239 |
3.6.1.9 | nucleotide diphosphatase |
Huh-7 cell |
- |
756172 |
4.1.2.4 | deoxyribose-phosphate aldolase |
Huh-7 cell |
among human cell lines, the highest deoxyribose-phosphate aldolase mRNA level and deoxyribose phosphate aldolase activity are observed in liver-derived Huh-7 cells |
747165 |
5.3.1.1 | triose-phosphate isomerase |
Huh-7 cell |
- |
746982 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
Huh-7 cell |
a hepatocyte-derived cellular carcinoma cell line |
727301 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
Huh-7 cell |
- |
672490, 674910, 715715 |
6.3.2.3 | glutathione synthase |
Huh-7 cell |
- |
705634 |
6.3.4.16 | carbamoyl-phosphate synthase (ammonia) |
Huh-7 cell |
hepatocarcinoma cell line, suppression of CPS1 expression occurs at the transcriptional level |
693935 |
6.3.4.2 | CTP synthase (glutamine hydrolysing) |
Huh-7 cell |
- |
744848 |